HKDC1 upregulation promotes glycolysis and disease progression, and confers chemoresistance onto gastric cancer
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15692
Abstract: There is increasing evidence that hexokinase is involved in cell proliferation and migration. However, the function of the hexokinase domain containing protein‐1 (HKDC1) in gastric cancer (GC) remains unclear. Immunohistochemistry analysis and big data mining… read more here.
Keywords: upregulation promotes; hkdc1 upregulation; hkdc1; gastric cancer ... See more keywords
HKDC1 Silencing Inhibits Proliferation and Glycolysis of Gastric Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Oncology"
DOI: 10.1155/2023/3876342
Abstract: Gastric cancer (GC) is the third most lethal and fifth most common cancer in the world. In a variety of cancers, the hexokinase domain component 1 (HKDC1) is carcinogenic. This study was to investigate into… read more here.
Keywords: proliferation glycolysis; hkdc1; cancer; gastric cancer ... See more keywords
Enterocyte HKDC1 Modulates Intestinal Glucose Absorption in Male Mice Fed a High-fat Diet
Sign Up to like & getrecommendations! Published in 2022 at "Endocrinology"
DOI: 10.1210/endocr/bqac050
Abstract: Abstract Hexokinase domain containing protein-1, or HKDC1, is a widely expressed hexokinase that is genetically associated with elevated 2-hour gestational blood glucose levels during an oral glucose tolerance test, suggesting a role for HKDC1 in… read more here.
Keywords: mice fed; hkdc1; high fat; fat diet ... See more keywords