PCR Array Profiling of Antiviral Genes in Human Embryonic Kidney Cells Expressing Human Coronavirus OC43 Structural and Accessory Proteins
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.728
Abstract: Background. Human coronaviruses (HCoV) OC43, 229E, NL63 and HKU1 commonly cause upper respiratory tract infections, but can also cause severe lower respiratory tract disease. Increased use of diagnostic assays for respiratory viruses has facilitated detection… read more here.
Keywords: hku1; hcov oc43; age; hcov ... See more keywords
Kallikrein 13 serves as a priming protease during infection by the human coronavirus HKU1
Sign Up to like & getrecommendations! Published in 2020 at "Science Signaling"
DOI: 10.1126/scisignal.aba9902
Abstract: The protease kallikrein 13 cleaves the spike protein of the human coronavirus HKU1 to facilitate viral entry. Priming viral entry Unlike SARS-CoV-2, the human coronavirus HKU1 normally causes relatively mild respiratory tract infections; however, it… read more here.
Keywords: hku1; hcov hku1; human coronavirus; infection ... See more keywords
Atypical Antibody Dynamics During Human Coronavirus HKU1 Infections
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.853410
Abstract: Human coronavirus HKU1 (HCoV-HKU1) is one of the four endemic coronaviruses. It has been suggested that there is a difference in incidence, with PCR-confirmed HCoV-NL63 and HCoV-OC43 infections occurring more commonly, whereas HCoV-HKU1 is the… read more here.
Keywords: hku1 infections; hcov hku1; hku1; antibody dynamics ... See more keywords
Origins and Evolution of Seasonal Human Coronaviruses
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DOI: 10.3390/v14071551
Abstract: Four seasonal human coronaviruses (sHCoVs) are endemic globally (229E, NL63, OC43, and HKU1), accounting for 5-30% of human respiratory infections. However, the epidemiology and evolution of these CoVs remain understudied due to their association with… read more here.
Keywords: origins evolution; evolution seasonal; seasonal human; hku1 ... See more keywords
A case of coronavirus HKU1 encephalitis.
Sign Up to like & getrecommendations! Published in 2020 at "Acta virologica"
DOI: 10.4149/av_2020_214
Abstract: Coronaviruses are widespread in nature and can infect several different species, causing mainly respiratory and enteric diseases. The respiratory involvement of human coronaviruses has been clearly established since the 1960s. Three of the six coronaviruses… read more here.
Keywords: hku1; hku1 encephalitis; case; coronavirus ... See more keywords