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   Articles with "hl60 cells" as a keyword



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FITC characterization of a cathepsin B‐responsive nanoprobe for report of differentiation of HL60 cells into macrophages

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recommendations! Published in 2021 at "Journal of Peptide Science"

DOI: 10.1002/psc.3371

Abstract: A cathepsin B (Cat B)‐responsive optical nanoprobe is designed and prepared for report of HL60 differentiation into macrophage. A peptide sequence FRFK is linked to fluorescein (FITC) via the distant amino group of its lysine… read more here.

Keywords: differentiation; report; hl60 cells; cathepsin ... See more keywords
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Antitumour effects of selected plant polyphenols, gallic acid and ellagic acid, on sensitive and multidrug‐resistant leukaemia HL60 cells

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recommendations! Published in 2019 at "Phytotherapy Research"

DOI: 10.1002/ptr.6317

Abstract: The aim of this study was to examine the antitumour effects of plant phenolic acids, gallic acid (GA) and ellagic acid (EA), on human promyelocytic leukaemia sensitive HL60 cell line and its resistant sublines exhibiting… read more here.

Keywords: gallic acid; antitumour effects; hl60 cells; acid ellagic ... See more keywords
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Non‐immunological toxicological mechanisms of metamizole‐associated neutropenia in HL60 cells

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recommendations! Published in 2019 at "Biochemical Pharmacology"

DOI: 10.1016/j.bcp.2019.01.011

Abstract: Graphical abstract Figure. No caption available. &NA; Metamizole is an analgesic and antipyretic, but can cause neutropenia and agranulocytosis. We investigated the toxicity of the metabolites N‐methyl‐4‐aminoantipyrine (MAA), 4‐aminoantipyrine (AA), N‐formyl‐4‐aminoantipyrine (FAA) and N‐acetyl‐4‐aminoantipyrine (AAA)… read more here.

Keywords: metamizole associated; aminoantipyrine; hemin; hl60 cells ... See more keywords
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Novel nitroaromatic compound activates autophagy and apoptosis pathways in HL60 cells.

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recommendations! Published in 2018 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2017.12.012

Abstract: N-(2-butanoyloxyethyl)-4-(chloromethyl)-3-nitrobenzamide (NBCN) is a nitroaromatic bioreducible compound with cytotoxic effects in cancer cell lines. The aim of this work was to investigate the molecular mechanisms involved in cell death promoted by NBCN in HL60 cells.… read more here.

Keywords: nitroaromatic compound; cytotoxic effects; compound activates; novel nitroaromatic ... See more keywords
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Relationship Between the Structure of Alkylpsoralens and Their Antiproliferative Activity in HL60 Cells

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recommendations! Published in 2022 at "AntiCancer Research"

DOI: 10.21873/anticanres.15654

Abstract: Background/Aim: As part of our continuing investigation in coumarin derivatives as potential anticancer substances, a series of alkylpsoralens were synthesized, and their antiproliferative activity was evaluated in leukemic HL60 cells. Materials and Methods: Alkylpsoralens were… read more here.

Keywords: relationship structure; structure alkylpsoralens; antiproliferative activity; hl60 cells ... See more keywords