Hypoxia‐inducing factor (HIF)‐1&agr;‐derived peptide capable of inducing cancer‐reactive cytotoxic T lymphocytes from HLA‐A24+ patients with renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2017.01.014
Abstract: &NA; Hypoxic tumor microenvironment makes cancer cells to be therapy‐resistant and hypoxia‐inducing factors (HIFs) play a central role in hypoxic adaptation. Especially, renal cell carcinoma (RCC) is often associated with von Hippel‐Lindau (VHL) gene mutations,… read more here.
Keywords: cancer; hla a24; rcc; hif agr ... See more keywords
Bispecific antibody targeting shared indel-derived neoantigen of APC
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DOI: 10.3389/fimmu.2025.1574958
Abstract: T cells play a pivotal role in cancer immunotherapy by recognizing tumor-specific neoantigens presented on HLA molecules, which are specifically expressed on cancer cells. While neoantigens are generally unique to individual cancers, certain neoantigens, known… read more here.
Keywords: hla a24; cancer; apc; antibody targeting ... See more keywords