Association of HLA‐DR‐DQ alleles, haplotypes, and diplotypes with type 1 diabetes in Saudis
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DOI: 10.1002/dmrr.3345
Abstract: Type 1 diabetes (T1D) is an autoimmune disease that affects many children worldwide. Genetic factors and environmental triggers play crucial interacting roles in the aetiology. This study aimed to assess the contribution of HLA‐DRB1‐DQA1‐DQB1 alleles,… read more here.
Keywords: alleles haplotypes; hla alleles; type diabetes; haplotypes diplotypes ... See more keywords
HLA‐HD: An accurate HLA typing algorithm for next‐generation sequencing data
Sign Up to like & getrecommendations! Published in 2017 at "Human Mutation"
DOI: 10.1002/humu.23230
Abstract: The accurate typing of human leukocyte antigen (HLA) alleles is critical for a variety of medical applications, such as genomic studies of multifactorial diseases, including immune system and inflammation‐related disorders, and donor selection in organ… read more here.
Keywords: hla alleles; accurate; hla typing; hla ... See more keywords
A case-control study of HLA alleles in Brazilian patients with Melkersson-Rosenthal syndrome.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of medical genetics"
DOI: 10.1016/j.ejmg.2020.103879
Abstract: Melkersson-Rosenthal syndrome (MRS) is a neuromucocutaneous disease that manifests by the triad of recurrent orofacial edema (frequently as cheilitis granulomatosa), relapsing facial paralysis and plicated tongue. The cause of MRS remains unknown, but genetic predisposal… read more here.
Keywords: hla alleles; control; study; hla ... See more keywords
P192 Association of C∗07:01 and C∗07:02 allelic variations with HLA-B alleles
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.252
Abstract: Aim There is a strong linkage disequilibrium between HLA-C and -B due to their genome proximity. The purpose of this study is to identify the associations between HLA-C∗07:01 and C∗07:02 allelic variations and HLA-B alleles… read more here.
Keywords: variations hla; p192 association; hla alleles; hla ... See more keywords
Tri-allelic expression of HLA gene in 46,XX/46,XY chimerism.
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DOI: 10.1016/j.trim.2018.12.004
Abstract: INTRODUCTION Chimerism is defined as coexistence of different cell lines in an individual. 46,XX/46,XY chimerism is very rare and exhibits broad range of clinical phenotypes. Most cases are detected at infancy or younger age due… read more here.
Keywords: hla alleles; chimerism; hla; expression hla ... See more keywords
Successful treatment of methazolamide‐induced toxic epidermal necrolysis in a Han Chinese patient with HLA‐B*59:01 and HLA‐Cw*01:02
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DOI: 10.1111/dth.13862
Abstract: Dear Editor, A 60-year-old man presented to our hospital's Emergency Department with multiple erythematous lesions, blisters on the trunk and limbs, and mucosal erosion. He had started taking methazolamide (100 mg/day) 3 weeks earlier for… read more here.
Keywords: hla alleles; methazolamide induced; hla; hla hla ... See more keywords
Association of class II HLA alleles with susceptibility to develop immune‐mediated diseases in Paraguayan patients
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Immunogenetics"
DOI: 10.1111/iji.12609
Abstract: Genetic and nongenetic factors are involved in the pathogenesis of immune‐mediated inflammatory diseases (IMIDs). The best‐known genetic factor for susceptibility to IMIDs is the human leukocyte antigen (HLA). The aim of the present study was… read more here.
Keywords: hla alleles; hla; paraguayan patients; class ... See more keywords
Assessment of HLA-A, HLA-DR, and HLA-DQ alleles in patients with pemphigus vulgaris from eastern of Turkey.
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DOI: 10.1111/jocd.13298
Abstract: BACKGROUND Pemphigus vulgaris (PV) is a chronic progressive autoimmune bullous disease caused by the interaction of pathogenic factors, genetic, and environmental factors. HLA alleles, which are considered as protective factors against disease or predisposing factors,… read more here.
Keywords: pemphigus vulgaris; eastern turkey; alleles patients; hla alleles ... See more keywords
Dual redundant sequencing strategy: Full‐length gene characterisation of 1056 novel and confirmatory HLA alleles
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DOI: 10.1111/tan.13057
Abstract: The high‐throughput department of DKMS Life Science Lab encounters novel human leukocyte antigen (HLA) alleles on a daily basis. To characterise these alleles, we have developed a system to sequence the whole gene from 5′‐… read more here.
Keywords: hla alleles; redundant sequencing; hla; strategy ... See more keywords
Characterization of two new HLA‐B alleles, HLA‐B*07:299 and HLA‐B*35:350
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DOI: 10.1111/tan.13195
Abstract: Two novel HLA‐B alleles, B*07:299 and B*35:350, were characterized by genomic full‐length sequencing. read more here.
Keywords: alleles hla; new hla; hla alleles; two new ... See more keywords
Identification of 33 novel HLA alleles in Arab potential bone marrow donors
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DOI: 10.1111/tan.13764
Abstract: Between 2008 and April 2018, we recruited more than 37 000 potential Arab donors to the Hadassah Bone Marrow Donor Registry, all of whom were typed for high resolution HLA‐A, ‐B, and ‐DRB1. In addition, more… read more here.
Keywords: novel hla; hla alleles; bone marrow; hla ... See more keywords