P236 An algorithm for overcoming autoantibody interference in solid phase HLA antibody testing
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.296
Abstract: Aim Autoimmunity introduces a variety of difficulties in interpretation of solid phase HLA antibody testing due to autoantibodies present in patient serum. However, because autoantibodies may be present without obvious symptoms or a clear diagnosis,… read more here.
Keywords: hla antibody; antibody; solid phase; phase hla ... See more keywords
Effect of Early Immunosuppression Therapy on De Novo Anti-Human-Leukocyte-Antigen Antibody After Kidney Transplantation.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.03.043
Abstract: The aim of the study was to investigate the effect of immunosuppression therapy early after kidney transplantation, particularly exposure of mycophenolic acid (MPA) and calcineurin inhibitor (CNI), on posttransplantation de novo HLA antibody production. METHODS… read more here.
Keywords: hla antibody; risk; antibody; effect ... See more keywords
Repeated Freezing and Thawing Does Not Affect HLA Antibody Titer
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation"
DOI: 10.1097/01.tp.0000543531.79282.83
Abstract: Introduction For deceased donor organ transplantations, we are not currently using virtual crossmatches (XMs) and preliminary negative T cell XMs are mandatory for kidney and pancreas allocation in Korea. Korean Network for Organ Sharing (KONOS)… read more here.
Keywords: hla antibody; hla; repeated freezing; freezing thawing ... See more keywords
Comparison of different luminex single antigen bead kits for memory B cell‐derived HLA antibody detection
Sign Up to like & getrecommendations! Published in 2021 at "Hla"
DOI: 10.1111/tan.14356
Abstract: Detection of HLA‐specific memory B cells can provide additional information on sensitization of alloantigen‐exposed individuals and refine immunological risk assessment. We have recently developed an assay enabling profiling of memory B cell‐derived HLA antibodies using… read more here.
Keywords: hla antibody; detection; memory cell; cell derived ... See more keywords
Clinical utility of serial serum dilutions for HLA antibody interpretation
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DOI: 10.1111/tan.14781
Abstract: Luminex single antigen bead (SAB) testing has increased the sensitivity and specificity of accurately identifying HLA antibodies, in support of all organ transplantation. However, as described in manufacturers' recommendation, the output of the assay, using… read more here.
Keywords: hla antibody; clinical utility; utility serial; serum dilutions ... See more keywords
Current Approaches to Desensitization in Solid Organ Transplantation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.686271
Abstract: Major advancements in the development of HLA antibody detection techniques and our understanding of the outcomes of solid organ transplant in the context of HLA antibody have occurred since the relevance of sensitization was first… read more here.
Keywords: hla antibody; desensitization solid; solid organ; organ transplantation ... See more keywords