HLA and kidney disease: from associations to mechanisms
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DOI: 10.1038/s41581-018-0057-8
Abstract: Since the first association between HLA and diseases of native kidneys was described almost 50 years ago, technological and conceptual advances in HLA biology and typing, together with better case ascertainment, have led to an… read more here.
Keywords: hla kidney; disease; hla; biology ... See more keywords
Distinct HLA associations of LGI1 and CASPR2-antibody diseases
Sign Up to like & getrecommendations! Published in 2018 at "Brain"
DOI: 10.1093/brain/awy109
Abstract: The mechanisms responsible for the generation of LGI1- or CASPR2-antibodies are unknown. Binks et al. describe two strikingly dichotomous HLA-associations, most significantly in HLA-DRB1*07:01 for LGI1, and HLA-DRB1*11:01 for CASPR2. Prediction of antigen-specific HLA-binding peptides… read more here.
Keywords: distinct hla; lgi1 caspr2; associations lgi1; hla ... See more keywords