Aortic root diameter is associated with HLA-B27: identifying the patient with ankylosing spondylitis at risk for aortic valve regurgitation
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology International"
DOI: 10.1007/s00296-021-05040-w
Abstract: To assess the association between the aortic root diameter in HLA-B27 positive (+) and HLA-B27 negative (−) ankylosing spondylitis (AS) patients from the CARDAS cohort. The CARDAS study is a cross-sectional study in AS patients… read more here.
Keywords: aortic root; hla b27; b27 patients; b27 ... See more keywords
Classification criteria for spondyloarthritis/HLA-B27-associated anterior uveitis.
Sign Up to like & getrecommendations! Published in 2021 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.03.049
Abstract: PURPOSE To determine classification criteria for spondyloarthritis/HLA-B27-associated anterior uveitis DESIGN: Machine learning of cases with spondyloarthritis/HLA-B27-associated anterior uveitis and 8 other anterior uveitides. METHODS Cases of anterior uveitides were collected in an informatics-designed preliminary database,… read more here.
Keywords: b27 associated; spondyloarthritis hla; anterior uveitis; hla b27 ... See more keywords
P175 Flow cytometry using monoclonal antibody for detection of HLA-B27: Analysis of ‘Gray Zone’ results for cross reactive antigens
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.235
Abstract: Aim HLA-B27 (associated with ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter’s syndrome) can be detected utilizing monoclonal antibodies. This assay is a simple qualitative two-color direct immunofluorescence flow cytometric method for rapid detection of the… read more here.
Keywords: gray zone; hla b27; cross reactive; hla ... See more keywords
Effectiveness and safety profile of anakinra in a HLA-B27 positive patient with multiple sclerosis-associated uveitis.
Sign Up to like & getrecommendations! Published in 2020 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2020.102152
Abstract: Multiple sclerosis (MS) is a chronic demyelinating disorder of central nervous system (CNS) leading to neurological disability. A wide variety of ophthalmic and neuro-ophthalmic manifestations have been associated with MS. Although this link is well… read more here.
Keywords: associated uveitis; hla b27; multiple sclerosis; b27 positive ... See more keywords
HLA-B27-related pathway mediates syndesmophyte formation in AS
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-019-0343-2
Abstract: Ankylosing spondylitis (AS) is characterized by the formation of syndesmophytes and occurs more frequently in HLA-B27+ individuals, but whether these two phenomena are related has been uncertain. According to the results of a new study,… read more here.
Keywords: hla b27; derived mscs; syndesmophyte formation; formation ... See more keywords
Younger age of onset and uveitis associated with HLA-B27 and delayed diagnosis in Thai patients with axial spondyloarthritis
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-93001-5
Abstract: To identify characteristics associated with HLA-B27, and to identify factors associated with delayed diagnosis in Thai patients with axial spondyloarthritis (axSpA). This cross-sectional study included Thai patients were diagnosed with axSpA by a rheumatologist at… read more here.
Keywords: b27; diagnosis; hla b27; associated hla ... See more keywords
Assessment of the Anti-inflammatory Effects of NORFLO® ORO in Acute Relapses of HLA-B27-associated Autoimmune Uveitis: A Multicenter, Randomized, Placebo-controlled, Double-blind Clinical Study.
Sign Up to like & getrecommendations! Published in 2022 at "Ocular immunology and inflammation"
DOI: 10.1080/09273948.2022.2039210
Abstract: BACKGROUND An effective therapy to reduce the number and severity of HLA-B27-related acute anterior uveitis (AAU) recurrences represents a clinical need. Curcumin is a promising therapeutic option in various inflammatory eye diseases. To enhance its… read more here.
Keywords: b27 related; study; assessment anti; uveitis ... See more keywords
A Multicenter Study of Clinical Features and HLA Typing in Japanese Patients With Ankylosing Spondylitis.
Sign Up to like & getrecommendations! Published in 2022 at "Modern rheumatology"
DOI: 10.1093/mr/roac008
Abstract: OBJECTIVES Due to the low prevalence of HLA-B27 and ankylosing spondylitis (AS) in Japan, rheumatologists have little experience with AS. We conducted a multicenter study to identify the characteristics and frequency of HLA-B types. METHODS… read more here.
Keywords: hla; multicenter study; japanese patients; ankylosing spondylitis ... See more keywords
E090 Secondary care collaborative service to reduce time to diagnosis in axial spondyloarthropathy: retrospective study from Leicester combined rheumatology-uveitis service
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead104.339
Abstract: The time from symptom onset to diagnosis of axial spondyloarthropathy (SpA) in the UK is 8.5 years. Previous studies show that half of patients with anterior uveitis are HLA-B27 positive and half of those have… read more here.
Keywords: uveitis; rheumatology; hla b27; diagnosis ... See more keywords
Human leucocyte antigen-B27 testing in clinical practice: a global perspective
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000946
Abstract: Purpose of review The association between human leucocyte antigen (HLA)-B27 and spondyloarthritis (SpA) was described half a century ago. New insights about pathophysiologic pathways and their role in bone formation were reported in recent years… read more here.
Keywords: b27; human leucocyte; leucocyte antigen; hla b27 ... See more keywords
HLA-B27 negative reactive arthritis versus HLA-B27 positive reactive arthritis: A retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030383
Abstract: Reactive arthritis (ReA) is defined as inflammatory arthritis secondary to an extra-articular infection with a key genetic background, HLA-B27. However, to date, the diagnosis and classification remain incomplete. The study focused on the similarities and… read more here.
Keywords: hla b27; reactive arthritis; arthritis; b27 negative ... See more keywords