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   Articles with "hla b27" as a keyword



Aortic root diameter is associated with HLA-B27: identifying the patient with ankylosing spondylitis at risk for aortic valve regurgitation

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recommendations! Published in 2021 at "Rheumatology International"

DOI: 10.1007/s00296-021-05040-w

Abstract: To assess the association between the aortic root diameter in HLA-B27 positive (+) and HLA-B27 negative (−) ankylosing spondylitis (AS) patients from the CARDAS cohort. The CARDAS study is a cross-sectional study in AS patients… read more here.

Keywords: aortic root; hla b27; b27 patients; b27 ... See more keywords
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Classification criteria for spondyloarthritis/HLA-B27-associated anterior uveitis.

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recommendations! Published in 2021 at "American journal of ophthalmology"

DOI: 10.1016/j.ajo.2021.03.049

Abstract: PURPOSE To determine classification criteria for spondyloarthritis/HLA-B27-associated anterior uveitis DESIGN: Machine learning of cases with spondyloarthritis/HLA-B27-associated anterior uveitis and 8 other anterior uveitides. METHODS Cases of anterior uveitides were collected in an informatics-designed preliminary database,… read more here.

Keywords: b27 associated; spondyloarthritis hla; anterior uveitis; hla b27 ... See more keywords

P175 Flow cytometry using monoclonal antibody for detection of HLA-B27: Analysis of ‘Gray Zone’ results for cross reactive antigens

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recommendations! Published in 2017 at "Human Immunology"

DOI: 10.1016/j.humimm.2017.06.235

Abstract: Aim HLA-B27 (associated with ankylosing spondylitis, juvenile rheumatoid arthritis, and Reiter’s syndrome) can be detected utilizing monoclonal antibodies. This assay is a simple qualitative two-color direct immunofluorescence flow cytometric method for rapid detection of the… read more here.

Keywords: gray zone; hla b27; cross reactive; hla ... See more keywords
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Effectiveness and safety profile of anakinra in a HLA-B27 positive patient with multiple sclerosis-associated uveitis.

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recommendations! Published in 2020 at "Multiple sclerosis and related disorders"

DOI: 10.1016/j.msard.2020.102152

Abstract: Multiple sclerosis (MS) is a chronic demyelinating disorder of central nervous system (CNS) leading to neurological disability. A wide variety of ophthalmic and neuro-ophthalmic manifestations have been associated with MS. Although this link is well… read more here.

Keywords: associated uveitis; hla b27; multiple sclerosis; b27 positive ... See more keywords

HLA-B27-related pathway mediates syndesmophyte formation in AS

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recommendations! Published in 2019 at "Nature Reviews Rheumatology"

DOI: 10.1038/s41584-019-0343-2

Abstract: Ankylosing spondylitis (AS) is characterized by the formation of syndesmophytes and occurs more frequently in HLA-B27+ individuals, but whether these two phenomena are related has been uncertain. According to the results of a new study,… read more here.

Keywords: hla b27; derived mscs; syndesmophyte formation; formation ... See more keywords
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Younger age of onset and uveitis associated with HLA-B27 and delayed diagnosis in Thai patients with axial spondyloarthritis

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-93001-5

Abstract: To identify characteristics associated with HLA-B27, and to identify factors associated with delayed diagnosis in Thai patients with axial spondyloarthritis (axSpA). This cross-sectional study included Thai patients were diagnosed with axSpA by a rheumatologist at… read more here.

Keywords: b27; diagnosis; hla b27; associated hla ... See more keywords

Assessment of the Anti-inflammatory Effects of NORFLO® ORO in Acute Relapses of HLA-B27-associated Autoimmune Uveitis: A Multicenter, Randomized, Placebo-controlled, Double-blind Clinical Study.

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recommendations! Published in 2022 at "Ocular immunology and inflammation"

DOI: 10.1080/09273948.2022.2039210

Abstract: BACKGROUND An effective therapy to reduce the number and severity of HLA-B27-related acute anterior uveitis (AAU) recurrences represents a clinical need. Curcumin is a promising therapeutic option in various inflammatory eye diseases. To enhance its… read more here.

Keywords: b27 related; study; assessment anti; uveitis ... See more keywords

Clinical Characteristics of HLA-B27-Associated Anterior Uveitis in a Finnish Population-Based Cohort

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recommendations! Published in 2024 at "Ocular Immunology and Inflammation"

DOI: 10.1080/09273948.2024.2360593

Abstract: ABSTRACT Purpose To evaluate the clinical characteristics, treatment outcomes and ocular complications in patients with HLA-B27-associated AU compared to those without HLA-B27. Methods From the population-based data of all adult patients with AU during 2009–2020… read more here.

Keywords: etiology; hla b27; b27 hla; b27 ... See more keywords

Pentraxin 3 is a Novel Inflammatory Marker of HLA-B27-associated Uveitis

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recommendations! Published in 2025 at "Ocular Immunology and Inflammation"

DOI: 10.1080/09273948.2025.2491565

Abstract: ABSTRACT Purpose Evidence exists that pentraxin 3 (PTX3) is involved in the pathogenesis of autoimmune diseases. The aim of this study was to analyze the levels of PTX3 in aqueous humor (AH) samples from patients… read more here.

Keywords: b27 associated; disease; hla b27; associated uveitis ... See more keywords

A Multicenter Study of Clinical Features and HLA Typing in Japanese Patients With Ankylosing Spondylitis.

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recommendations! Published in 2022 at "Modern rheumatology"

DOI: 10.1093/mr/roac008

Abstract: OBJECTIVES Due to the low prevalence of HLA-B27 and ankylosing spondylitis (AS) in Japan, rheumatologists have little experience with AS. We conducted a multicenter study to identify the characteristics and frequency of HLA-B types. METHODS… read more here.

Keywords: hla; multicenter study; japanese patients; ankylosing spondylitis ... See more keywords

E090 Secondary care collaborative service to reduce time to diagnosis in axial spondyloarthropathy: retrospective study from Leicester combined rheumatology-uveitis service

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recommendations! Published in 2023 at "Rheumatology"

DOI: 10.1093/rheumatology/kead104.339

Abstract: The time from symptom onset to diagnosis of axial spondyloarthropathy (SpA) in the UK is 8.5 years. Previous studies show that half of patients with anterior uveitis are HLA-B27 positive and half of those have… read more here.

Keywords: uveitis; rheumatology; hla b27; diagnosis ... See more keywords