Nomenclature and Serology of HLA Class I and Class II Alleles
Sign Up to like & getrecommendations! Published in 2017 at "Current Protocols in Immunology"
DOI: 10.1002/cpim.32
Abstract: This overview presents nomenclature and serology information on human leucocyte antigens, or HLA molecules, which are encoded by a cluster of genes linked on the short arm of chromosome 6. This region is known as… read more here.
Keywords: class; serology; hla class; serology hla ... See more keywords
Association of HLA class I and II genes with Middle East respiratory syndrome coronavirus infection in Koreans
Sign Up to like & getrecommendations! Published in 2021 at "Immunity"
DOI: 10.1002/iid3.541
Abstract: Middle East Respiratory Syndrome (MERS) caused by MERS‐coronavirus (CoV) is a lower respiratory tract disease characterized by a high mortality rate. MERS‐CoV spread from Saudi Arabia to other countries, including South Korea. Dysfunction of the… read more here.
Keywords: hla; hla class; respiratory syndrome; association hla ... See more keywords
Identification of novel variants in HLA class II region related to HLA DPB1 expression and disease progression in patients with chronic hepatitis C
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Medical Virology"
DOI: 10.1002/jmv.24814
Abstract: Recent genome‐wide studies have demonstrated that HLA class II gene may play an important role in viral hepatitis. We studied genetic polymorphism and RNA expression of HLA class II genes in HCV‐related liver diseases. The… read more here.
Keywords: dpb1; expression; group; hla class ... See more keywords
Data‐Independent Acquisition of HLA Class I Peptidomes on the Q Exactive Mass Spectrometer Platform
Sign Up to like & getrecommendations! Published in 2017 at "PROTEOMICS"
DOI: 10.1002/pmic.201700177
Abstract: The characterization of peptides presented by human leukocyte antigen (HLA) class I molecules is crucial for understanding immune processes, biomarker discovery, and the development of novel immunotherapies or vaccines. Mass spectrometry allows the direct identification… read more here.
Keywords: data independent; acquisition; mass; hla class ... See more keywords
Database search engines and target database features impinge upon the identification of post-translationally cis-spliced peptides in HLA class I immunopeptidomes.
Sign Up to like & getrecommendations! Published in 2022 at "Proteomics"
DOI: 10.1002/pmic.202100226
Abstract: Unconventional epitopes presented by HLA class I complexes are emerging targets for T cell targeted immunotherapies. Their identification by mass spectrometry required development of novel methods to cope with the large number of theoretical candidates.… read more here.
Keywords: cis spliced; hla class; spliced peptides; class immunopeptidomes ... See more keywords
Tumor mutational load, CD8+ T cells, expression of PD-L1 and HLA class I to guide immunotherapy decisions in NSCLC patients
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02506-x
Abstract: A minority of NSCLC patients benefit from anti-PD1 immune checkpoint inhibitors. A rational combination of biomarkers is needed. The objective was to determine the predictive value of tumor mutational load (TML), CD8+ T cell infiltration,… read more here.
Keywords: cd8; class; nsclc patients; hla class ... See more keywords
Human leukocyte antigen expression in paired primary lung tumors and brain metastases in non-small cell lung cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02677-7
Abstract: Loss of human leukocyte antigen (HLA) class 1 expression is a mechanism of tumor immune escape and may contribute to resistance to immunotherapy. Patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors… read more here.
Keywords: brain metastases; hla class; expression; brain ... See more keywords
Contribution of HLA class II genes, DRB4*01:01, DRB1*07:01, and DQB1*03:03:2 to clinical features of Vitiligo disease in Iranian population.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular biology reports"
DOI: 10.1007/s11033-021-06855-3
Abstract: BACKGROUND Vitiligo is a multifactorial depigmentation condition, which is due to skin melanocyte destruction. Increased expression of HLA class II genes in patients with pre-lesions of Vitiligo suggests a crucial role for the participation of… read more here.
Keywords: vitiligo; drb4 drb1; drb1 dqb1; hla class ... See more keywords
Fine mapping of the major histocompatibility complex (MHC) in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suggests involvement of both HLA class I and class II loci
Sign Up to like & getrecommendations! Published in 2021 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2021.08.219
Abstract: The etiology of myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is unknown, but involvement of the immune system is one of the proposed underlying mechanisms. Human leukocyte antigen (HLA) associations are hallmarks of immune-mediated and autoimmune diseases.… read more here.
Keywords: class; cfs; myalgic encephalomyelitis; hla class ... See more keywords
HLA class-I-peptide stability mediates CD8+ T cell immunodominance hierarchies and facilitates HLA-associated immune control of HIV
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DOI: 10.1016/j.celrep.2021.109378
Abstract: Summary Defining factors that govern CD8+ T cell immunodominance is critical for the rational design of vaccines for viral pathogens. Here, we assess the contribution of human leukocyte antigen (HLA) class-I-peptide stability for 186 optimal… read more here.
Keywords: cd8 cell; cell; class peptide; hla class ... See more keywords
P132 Differential HLA-C expression in caucasians: Useful data from direct HLA-protein measurements in 188 healthy German donors
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.192
Abstract: Aim The established variability of HLA-C expression on cell surface, although already investigated in African Americans by Apps et al. Science 2013(1), has not been yet accordingly researched in Caucasians. Furthermore, the possibility that HLA-C… read more here.
Keywords: class expression; hla expression; hla class; hla ... See more keywords