How HLA diversity is apportioned: influence of selection and relevance to transplantation
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DOI: 10.1098/rstb.2020.0420
Abstract: In his 1972 paper ‘The apportionment of human diversity’, Lewontin showed that, when averaged over loci, genetic diversity is predominantly attributable to differences among individuals within populations. However, selection can alter the apportionment of diversity… read more here.
Keywords: hla; hla loci; hla diversity; diversity ... See more keywords
The HLA diversity of the Anthony Nolan register
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DOI: 10.1111/tan.14127
Abstract: While the success of allogeneic stem cell transplantation depends on a high degree of HLA compatibility between donor and patient, finding a suitable donor remains challenging due to the hyperpolymorphic nature of HLA genes. We… read more here.
Keywords: diversity; hla diversity; nolan register; anthony nolan ... See more keywords