Consequences of HLA‐associated mutations in HIV‐1 subtype C Nef on HLA‐I downregulation ability
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DOI: 10.1002/jmv.25676
Abstract: Identification of CD8+ T lymphocyte (CTL) escape mutations that compromise the pathogenic functions of the Nef protein may be relevant for an HIV‐1 attenuation‐based vaccine. Previously, HLA‐associated mutations 102H, 105R, 108D, and 199Y were individually… read more here.
Keywords: hla downregulation; downregulation ability; downregulation; nef ... See more keywords
Combination of Expanded Allogeneic NK Cells and T Cell-Based Immunotherapy Exert Enhanced Antitumor Effects
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DOI: 10.3390/cancers15010251
Abstract: Simple Summary The clinical efficacy of neoantigen-reactive tumor-infiltrating lymphocytes and T cell receptor-engineered T cells (TCR-T) therapy is primarily attributed to the effective CD8+ T cell responses that are limited to HLA-I presenting tumor-specific antigens.… read more here.
Keywords: cell based; cell; immunotherapy; combination ... See more keywords