SU93 REPLICATION OF TWO INDEPENDENT LOCI IN HLA-DQB1 AND HLA-B CONTRIBUTING TO THE RISK OF CLOZAPINE-INDUCED AGRANULOCYTOSIS
Sign Up to like & getrecommendations! Published in 2019 at "European Neuropsychopharmacology"
DOI: 10.1016/j.euroneuro.2017.08.282
Abstract: Background The atypical antipsychotic drug clozapine is the only effective drug for treatment-resistant schizophrenia, but also bears the risk of inducing severe adverse drug responses like neutropenia and agranulocytosis. Agranulocytosis and neutropenia occurs in about… read more here.
Keywords: clozapine; induced agranulocytosis; hla dqb1; clozapine induced ... See more keywords
P058 The importance of complete HLA-DQB1 sequences when typing beyond exon 2
Sign Up to like & getrecommendations! Published in 2018 at "Human Immunology"
DOI: 10.1016/j.humimm.2018.07.116
Abstract: Aim This study examined the variation observed when typing exons 2 + 3 of HLA-DQB1 using reverse sequence specific oligonucleotides (rSSO) as compared to typing exon 2 alone in volunteers from an unrelated hematopoietic stem cell donor… read more here.
Keywords: dqb1 sequences; one lambda; p058 importance; hla dqb1 ... See more keywords
A 10-gene prognostic signature points to LIMCH1 and HLA-DQB1 as important players in aggressive cervical cancer disease
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DOI: 10.1038/s41416-021-01305-0
Abstract: Background Advanced cervical cancer carries a particularly poor prognosis, and few treatment options exist. Identification of effective molecular markers is vital to improve the individualisation of treatment. We investigated transcriptional data from cervical carcinomas related… read more here.
Keywords: hla dqb1; cervical cancer; disease; signature ... See more keywords
Allele frequency and the associations of HLA-DRB1 and HLA-DQB1 polymorphisms with pemphigus subtypes and disease severity
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DOI: 10.1097/md.0000000000028855
Abstract: Abstract Pemphigus is a rare, devastating, bullous autoimmune disease that damages the skin and mucous membranes, and has high morbidity and mortality. Studies have shown associations of pemphigus vulgaris (PV) and pemphigus foliaceus (PF) with… read more here.
Keywords: hla dqb1; pemphigus subtypes; polymorphisms pemphigus; hla drb1 ... See more keywords
Association of HLA‐DQB1*03:03 with pityriasis rosea in Chinese patients
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DOI: 10.1111/ced.13313
Abstract: The association of human leucocyte antigen (HLA) with a variety of diseases has been described, especially with various autoimmune diseases. However, there are few studies on the association between HLA and pityriasis rosea (PR). read more here.
Keywords: hla dqb1; association hla; pityriasis rosea;
HLA‐DQB1*02 allele in children with celiac disease: Potential usefulness for screening strategies
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Immunogenetics"
DOI: 10.1111/iji.12441
Abstract: Through a retrospective analysis of a real‐life cohort of children with celiac disease (CD), who underwent HLA‐DQ genotyping, we supported our previous findings indicating the presence of HLA‐DQB1*02 allele in at least 90%–95% of pediatric… read more here.
Keywords: celiac disease; dqb1 allele; children celiac; hla dqb1 ... See more keywords
Retrospective cohort study of hypersomnias of central origin from two Australian tertiary sleep disorders services.
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DOI: 10.1111/imj.15920
Abstract: BACKGROUND Hypersomnias of central origin (HOCO) are diverse in origin and symptomatology and remain poorly described in an Australian population. We hypothesized that the rate of human leukocyte antigen (HLA) DQB1*0602 positivity in the Australian… read more here.
Keywords: dqb1 0602; hla dqb1; central origin; origin ... See more keywords
HLA‐DQB1*03:01:34, a novel allele, which has arisen by silent mutation in codon 87
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DOI: 10.1111/tan.12935
Abstract: HLA‐DQB1*03:01:34 has one nucleotide change from HLA‐ DQB1*03:01:01 at nucleotide 357 bp where C>A in exon 2. read more here.
Keywords: dqb1 novel; hla dqb1; novel allele; hla ... See more keywords
Characterization of the novel HLA‐DQB1*05:155 allele by sequencing‐based typing
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DOI: 10.1111/tan.13142
Abstract: HLA‐DQB1*05:155 differs from HLA‐DQB1*05:01:01 by one nucleotide substitution at position 474 (G>C). read more here.
Keywords: characterization novel; dqb1 155; 155 allele; hla dqb1 ... See more keywords
Characterization of the novel HLA‐DQB1*06:02:29 allele by sequencing‐based typing
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DOI: 10.1111/tan.13271
Abstract: HLA‐DQB1*06:02:29 differs from HLA‐DQB1*06:02:01:01 by one nucleotide substitution at position 408 (C > T). read more here.
Keywords: characterization novel; dqb1 allele; hla dqb1; hla ... See more keywords
Characterization of the novel HLA‐DQB1*03:279 allele by sequencing‐based typing
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DOI: 10.1111/tan.13272
Abstract: HLA‐DQB1*03:279 differs from HLA‐DQB1*03:02:01:01 by one nucleotide substitution at position 218 (A>T). read more here.
Keywords: characterization novel; hla dqb1; hla; novel hla ... See more keywords