DSA in solid organ transplantation: is it a matter of specificity, amount, or functional characteristics?
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Organ Transplantation"
DOI: 10.1097/mot.0000000000001006
Abstract: Purpose of review The present review describes the clinical relevance of human leukocyte antigen (HLA) donor-specific antibodies (HLA-DSAs) as biomarkers of alloimmunity and summarizes recent improvements in their characterization that provide insights into immune risk… read more here.
Keywords: organ transplantation; hla dsas; risk; hla ... See more keywords
Microvascular Inflammation of the Renal Allograft: A Reappraisal of the Underlying Mechanisms
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.864730
Abstract: Antibody-mediated rejection (ABMR) is associated with poor transplant outcomes and was identified as a leading cause of graft failure after kidney transplantation. Although the hallmark histological features of ABMR (ABMRh), i.e., microvascular inflammation (MVI), usually… read more here.
Keywords: inflammation; allograft reappraisal; hla dsas; microvascular inflammation ... See more keywords