Analysis of HLA-G protein expression in leprosy
Sign Up to like & getrecommendations! Published in 2020 at "Immunogenetics"
DOI: 10.1007/s00251-020-01168-4
Abstract: The aim of this study was to evaluate the expression of human leukocyte antigen G (HLA-G) in leprosy. Biopsy and serum samples were collected from 18 patients presenting with leprosy and from healthy controls. Samples… read more here.
Keywords: protein expression; analysis hla; hla expression; hla protein ... See more keywords
Cytokine stimulation of the choriocarcinoma cell line JEG-3 leads to alterations in the HLA-G expression profile.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2020.104110
Abstract: The checkpoint molecule human leukocyte antigen (HLA)-G has restricted tissue expression, and plays a role in the establishment of maternal tolerance to the semi-allogenic fetus during pregnancy by expression on the trophoblast cells in the… read more here.
Keywords: cell line; choriocarcinoma cell; hla expression; expression ... See more keywords
The prognostic benefit of tumour-infiltrating Natural Killer cells in endometrial cancer is dependent on concurrent overexpression of Human Leucocyte Antigen-E in the tumour microenvironment.
Sign Up to like & getrecommendations! Published in 2017 at "European journal of cancer"
DOI: 10.1016/j.ejca.2017.09.008
Abstract: BACKGROUND Human Leucocyte Antigen- E (HLA-E) has been reported as both a positive and negative prognostic marker in cancer. This apparent discrepancy may be due to opposing actions of HLA-E on tumour-infiltrating immune cells. Therefore,… read more here.
Keywords: cancer; human leucocyte; hla expression; prognostic benefit ... See more keywords
P132 Differential HLA-C expression in caucasians: Useful data from direct HLA-protein measurements in 188 healthy German donors
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.192
Abstract: Aim The established variability of HLA-C expression on cell surface, although already investigated in African Americans by Apps et al. Science 2013(1), has not been yet accordingly researched in Caucasians. Furthermore, the possibility that HLA-C… read more here.
Keywords: class expression; hla expression; hla class; hla ... See more keywords
Human Herpes simplex 1 virus infection of endometrial decidual tissue-derived MSC alters HLA-G expression and immunosuppressive functions.
Sign Up to like & getrecommendations! Published in 2018 at "Human immunology"
DOI: 10.1016/j.humimm.2018.08.006
Abstract: OBJECTIVES Mesenchymal stromal/stem cells have immunosuppressive functions. Our previous results demonstrated that one of the players of this immunomodulation can be ascribed to the Human Leukocyte Antigen-G. HLA-G, a non classical HLA class I antigen,… read more here.
Keywords: edt msc; immunosuppressive functions; infection; hla expression ... See more keywords
Enhanced HLA-DR expression on T-lymphocytes from patients in early stages of non-surgical sepsis.
Sign Up to like & getrecommendations! Published in 2019 at "Medicina clinica"
DOI: 10.1016/j.medcli.2018.07.007
Abstract: INTRODUCTION Early detection of sepsis is a critical step to improve patient's survival and cellular markers effective diagnosis tools. The aim of this work was to evaluate HLA-DR expression on peripheral T-lymphocytes (CD3+), a marker… read more here.
Keywords: sepsis; hla expression; enhanced hla; expression ... See more keywords
Mitochondrial DNA webs
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0058-6
Abstract: The expression of HLA alleles varies and can influence adaptive immune responses beyond the HLA peptide-presentation ability. In Science, Carrington and colleagues show that allelic variation that increases HLA-A expression results in an impaired ability… read more here.
Keywords: hla expression; dna webs; hla; expression ... See more keywords
HLA-G expression in melanomas
Sign Up to like & getrecommendations! Published in 2021 at "International Reviews of Immunology"
DOI: 10.1080/08830185.2020.1869732
Abstract: Abstract Objective Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule involved in inducing tolerance at the feto-maternal interface and in escape of immune response by tumor cells. The aim of the… read more here.
Keywords: expression; hla expression; expression melanomas; immunology ... See more keywords
NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts
Sign Up to like & getrecommendations! Published in 2017 at "Biology of Reproduction"
DOI: 10.1093/biolre/iox009
Abstract: Abstract During pregnancy, fetal extravillous trophoblasts (EVT) play a key role in the regulation of maternal T cell and NK cell responses. EVT display a unique combination of human leukocyte antigens (HLA); EVT do not… read more here.
Keywords: hla expression; jeg3; hla; expression ... See more keywords
HLA‐DR+ NK cells are mostly characterized by less mature phenotype and high functional activity
Sign Up to like & getrecommendations! Published in 2018 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.1032
Abstract: NK cells change their phenotype and functional characteristics during activation. In this work, we searched for a relationship of HLA‐DR expression with differentiation stages and functional activity of NK cells ex vivo and stimulated in… read more here.
Keywords: hla expression; cells mostly; hla; expression ... See more keywords
Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-116828
Abstract: HLA-E is a non-classical major histocompatibility complex (MHC) class I molecule characterized by limited polymorphism in contrast to its class I counterparts HLA-A, -B, and -C. HLA-E elicits an inhibitory signal via its interactions with… read more here.
Keywords: expression; hla expression; consultancy; research funding ... See more keywords