Identification of non-HLA genes associated with development of islet autoimmunity and type 1 diabetes in the prospective TEDDY cohort.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of autoimmunity"
DOI: 10.1016/j.jaut.2017.12.008
Abstract: Traditional linkage analysis and genome-wide association studies have identified HLA and a number of non-HLA genes as genetic factors for islet autoimmunity (IA) and type 1 diabetes (T1D). However, the relative risk associated with previously… read more here.
Keywords: risk; non hla; hla genes; islet ... See more keywords
Full-length HLA sequencing in adult T cell leukemia–lymphoma uncovers multiple gene alterations
Sign Up to like & getrecommendations! Published in 2021 at "Leukemia"
DOI: 10.1038/s41375-021-01403-1
Abstract: To the Editor: Adult T cell leukemia–lymphoma (ATL) is a peripheral T cell lymphoid malignancy caused by human T cell leukemia virus type 1 (HTLV-1). The clinical subtypes of ATL are closely associated with its… read more here.
Keywords: hla genes; hla; non atl; atl cells ... See more keywords
Effect of bisphenol A on alterations of ICAM-1 and HLA-G genes expression and DNA methylation profiles in cumulus cells of infertile women with poor response to ovarian stimulation
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-87175-1
Abstract: This study aimed to investigate the relationship between follicular fluid Bisphenol A (BPA) concentrations with alterations of ICAM-1 and HLA-G genes and proteins expression as well as methylation profiles in the cumulus cells of poor… read more here.
Keywords: methylation; hla genes; group; icam hla ... See more keywords
Polymorphisms in HLA‐DQ genes, together with age, sex, and Helicobacter pylori infection, as potential biomarkers for the early diagnosis of gastric cancer
Sign Up to like & getrecommendations! Published in 2017 at "Helicobacter"
DOI: 10.1111/hel.12326
Abstract: Polymorphisms in inflammation‐related genes are factors associated with the development of gastroduodenal diseases in Helicobacter pylori‐infected individuals. read more here.
Keywords: polymorphisms hla; hla genes; genes together; age sex ... See more keywords
Expression estimation and eQTL mapping for HLA genes with a personalized pipeline
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1008091
Abstract: The HLA (Human Leukocyte Antigens) genes are well-documented targets of balancing selection, and variation at these loci is associated with many disease phenotypes. Variation in expression levels also influences disease susceptibility and resistance, but little… read more here.
Keywords: eqtl mapping; hla genes; hla; expression ... See more keywords
Construction of an HLA Classifier for Early Diagnosis, Prognosis, and Recognition of Immunosuppression in Sepsis by Multiple Transcriptome Datasets
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.870657
Abstract: Background: Sepsis is a clinical syndrome, due to a dysregulated inflammatory response to infection. Accumulating evidence shows that human leukocyte antigen (HLA) genes play a key role in the immune responses to sepsis. Nevertheless, the… read more here.
Keywords: sepsis; hla; hla classifier; expression ... See more keywords