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Published in 2024 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2024.1037
Abstract: Importance The HLA-B*15:02 allele has been associated with an increased risk of carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in specific Asian populations (including Han Chinese, Malaysian, Thai, and Vietnamese individuals). While HLA-B*15:02 genotype testing…
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Keywords:
asian australian;
hla;
genotyping asian;
hla genotyping ... See more keywords
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Published in 2017 at "British Journal of Haematology"
DOI: 10.1111/bjh.14385
Abstract: Lack of reliable laboratory parameters is the main challenge in the management of fetal and neonatal alloimmune thrombocytopenia (FNAIT). Despite the long‐known association between the HLA‐DRB3*01:01 allele and human platelet antigen 1a (HPA‐1a) alloimmunisation, maternal…
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Keywords:
fetal neonatal;
alloimmune thrombocytopenia;
hla;
hla genotyping ... See more keywords
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Published in 2020 at "HLA"
DOI: 10.1111/tan.13806
Abstract: HLA‐E, a class I nonclassical HLA molecule, is expressed in all tissues and is involved in the regulation of both innate (by interaction with the CD94/NKG2 receptor expressed mainly in NK cells) and adaptive immunity…
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Keywords:
relevance kidney;
genotyping relevance;
hla;
hla genotyping ... See more keywords
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Published in 2021 at "HLA"
DOI: 10.1111/tan.14259
Abstract: The International HLA and Immunogenetics Workshops (IHIWs) have fostered international collaborations of researchers and experts in the fields of HLA, histocompatibility and immunology. These IHIW collaborations have comprised many projects focused on achieving a variety…
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Keywords:
18th ihiw;
reference;
hla genotyping;
reference sequences ... See more keywords
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Published in 2025 at "HLA"
DOI: 10.1111/tan.70442
Abstract: HLA molecules play a central role in the adaptive immune response. Their high polymorphism influences individual susceptibility to various autoimmune diseases and certain drug‐induced hypersensitivities. In France, HLA genotyping is classified as a medical genetics…
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Keywords:
hla;
hla dqb1;
hla genotyping;
immunogenetics ... See more keywords
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Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1551173
Abstract: Introduction Accurate human leukocyte antigen (HLA) genotyping is critical for organ transplantation to ensure donor-recipient compatibility. Conventional methods, such as sequence-based typing (SBT), often face challenges in resolving allelic ambiguities, particularly in highly polymorphic regions…
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Keywords:
hla genotyping;
multiplex pcr;
high resolution;
hla ... See more keywords