Articles with "hla genotyping" as a keyword



Economic Evaluation of HLA-B*15:02 Genotyping for Asian Australian Patients With Epilepsy.

Sign Up to like & get
recommendations!
Published in 2024 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2024.1037

Abstract: Importance The HLA-B*15:02 allele has been associated with an increased risk of carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in specific Asian populations (including Han Chinese, Malaysian, Thai, and Vietnamese individuals). While HLA-B*15:02 genotype testing… read more here.

Keywords: asian australian; hla; genotyping asian; hla genotyping ... See more keywords

Maternal HLA genotyping is not useful for predicting severity of fetal and neonatal alloimmune thrombocytopenia

Sign Up to like & get
recommendations!
Published in 2017 at "British Journal of Haematology"

DOI: 10.1111/bjh.14385

Abstract: Lack of reliable laboratory parameters is the main challenge in the management of fetal and neonatal alloimmune thrombocytopenia (FNAIT). Despite the long‐known association between the HLA‐DRB3*01:01 allele and human platelet antigen 1a (HPA‐1a) alloimmunisation, maternal… read more here.

Keywords: fetal neonatal; alloimmune thrombocytopenia; hla; hla genotyping ... See more keywords

HLA‐E genotyping and its relevance in kidney transplantation outcome

Sign Up to like & get
recommendations!
Published in 2020 at "HLA"

DOI: 10.1111/tan.13806

Abstract: HLA‐E, a class I nonclassical HLA molecule, is expressed in all tissues and is involved in the regulation of both innate (by interaction with the CD94/NKG2 receptor expressed mainly in NK cells) and adaptive immunity… read more here.

Keywords: relevance kidney; genotyping relevance; hla; hla genotyping ... See more keywords

Standard Reference Sequences for Submission of HLA Genotyping for the 18th IHIW.

Sign Up to like & get
recommendations!
Published in 2021 at "HLA"

DOI: 10.1111/tan.14259

Abstract: The International HLA and Immunogenetics Workshops (IHIWs) have fostered international collaborations of researchers and experts in the fields of HLA, histocompatibility and immunology. These IHIW collaborations have comprised many projects focused on achieving a variety… read more here.

Keywords: 18th ihiw; reference; hla genotyping; reference sequences ... See more keywords

Guidelines From the French‐Speaking Society for Histocompatibility and Immunogenetics (SFHI) for Harmonisation of HLA Genotyping in Autoimmune Diseases, Drug Hypersensitivity and Pharmacogenetics

Sign Up to like & get
recommendations!
Published in 2025 at "HLA"

DOI: 10.1111/tan.70442

Abstract: HLA molecules play a central role in the adaptive immune response. Their high polymorphism influences individual susceptibility to various autoimmune diseases and certain drug‐induced hypersensitivities. In France, HLA genotyping is classified as a medical genetics… read more here.

Keywords: hla; hla dqb1; hla genotyping; immunogenetics ... See more keywords

Optimized multiplex PCR-NGS for comprehensive HLA genotyping in Chinese populations: resolving ambiguities at high resolution

Sign Up to like & get
recommendations!
Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1551173

Abstract: Introduction Accurate human leukocyte antigen (HLA) genotyping is critical for organ transplantation to ensure donor-recipient compatibility. Conventional methods, such as sequence-based typing (SBT), often face challenges in resolving allelic ambiguities, particularly in highly polymorphic regions… read more here.

Keywords: hla genotyping; multiplex pcr; high resolution; hla ... See more keywords