Reducing severe cutaneous adverse and type B adverse drug reactions using pre‐stored human leukocyte antigen genotypes
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12098
Abstract: Abstract Background Several type B adverse drug reactions (ADRs), especially severe cutaneous adverse reactions (SCARs), are associated with particular human leukocyte antigen (HLA) genotypes. However, pre‐stored HLA information obtained from other clinical workups has not… read more here.
Keywords: hla hla; hla; pre stored; risk ... See more keywords
The impact of human leukocyte antigen mismatch on recipient outcomes in living‐donor liver transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Liver Transplantation"
DOI: 10.1002/lt.26511
Abstract: Donor–recipient human leukocyte antigen (HLA) compatibility has not been considered to significantly affect liver transplantation (LT) outcomes; however, its significance in living‐donor LT (LDLT), which is mostly performed between blood relatives, remains unclear. This retrospective… read more here.
Keywords: recipient; hla hla; hla; mismatch ... See more keywords
Computational investigation of peptide binding stabilities of HLA-B*27 and HLA-B*44 alleles
Sign Up to like & getrecommendations! Published in 2020 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2019.107195
Abstract: Major Histocompatibility Complex (MHC) is a cell surface glycoprotein that binds to foreign antigens and presents them to T lymphocyte cells on the surface of Antigen Presenting Cells (APCs) for appropriate immune recognition. Recently, studies… read more here.
Keywords: peptide binding; investigation peptide; binding stabilities; hla ... See more keywords
Exploring the ancestry and admixture of Mexican Oaxaca Mestizos from Southeast Mexico using next-generation sequencing of 11 HLA loci.
Sign Up to like & getrecommendations! Published in 2019 at "Human immunology"
DOI: 10.1016/j.humimm.2019.01.004
Abstract: The Mestizos of Oaxaca resulted from the admixture of Zapotecan Natives with Spaniards and Africans. We selected 112 donors from Oaxaca and applied next-generation sequencing to characterize exon and intron variants in complete or extended… read more here.
Keywords: mestizos; hla; hla hla; hla loci ... See more keywords
Maternal and child human leukocyte antigens in congenital cytomegalovirus infection.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2018.01.002
Abstract: Congenital Cytomegalovirus infection (cCMV) is the most common cause of congenital infections worldwide causing permanent long-term impairment (LTI). cCMV immunopathogenesis remains largely unknown due to the complex interplay between viral, maternal, placental and child factors.… read more here.
Keywords: congenital cytomegalovirus; hla; viral load; hla hla ... See more keywords
Association of HLA-B and HLA-DRB1 polymorphisms with antithyroid drug-induced agranulocytosis in a Han population from northern China
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-12350-2
Abstract: Antithyroid drug (ATD)-induced agranulocytosis is associated with human leukocyte antigen (HLA) and nearby genes in Southeast Asian and European populations. The susceptibility of the Han population from northern China to ATD-induced agranulocytosis has not been… read more here.
Keywords: induced agranulocytosis; hla drb1; hla; hla hla ... See more keywords
HLA-B, HLA-C and KIR improve the predictive value of IFNL3 for Hepatitis C spontaneous clearance
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17531-7
Abstract: IFNL3 is the strongest predictor of spontaneous resolution (SR) of hepatitis C virus (HCV), however, consideration of IFNL3 genotype alone is of limited clinical value for the prediction of SR or chronic HCV infection. The… read more here.
Keywords: hla; hla hla; ifnl3; predictive value ... See more keywords
HLA*LA—HLA typing from linearly projected graph alignments
Sign Up to like & getrecommendations! Published in 2019 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btz235
Abstract: Abstract Summary HLA*LA implements a new graph alignment model for human leukocyte antigen (HLA) type inference, based on the projection of linear alignments onto a variation graph. It enables accurate HLA type inference from whole-genome… read more here.
Keywords: hla typing; hla; graph; linearly projected ... See more keywords
NLRP2 is a suppressor of NF-B signaling and HLA-C expression in human trophoblasts
Sign Up to like & getrecommendations! Published in 2017 at "Biology of Reproduction"
DOI: 10.1093/biolre/iox009
Abstract: Abstract During pregnancy, fetal extravillous trophoblasts (EVT) play a key role in the regulation of maternal T cell and NK cell responses. EVT display a unique combination of human leukocyte antigens (HLA); EVT do not… read more here.
Keywords: hla expression; jeg3; hla; expression ... See more keywords
HLA Class Ib-receptor interactions during embryo implantation and early pregnancy.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction update"
DOI: 10.1093/humupd/dmac007
Abstract: BACKGROUND Although the immune system intuitively must have an important role in embryo implantation and in the achievement of a pregnancy, the molecular details have for long been controversial. The role of the human leukocyte… read more here.
Keywords: hla class; hla hla; hla; implantation ... See more keywords
HLA-A and HLA-B genes are involved in the pathogenesis of IBS
Sign Up to like & getrecommendations! Published in 2023 at "Medicine"
DOI: 10.1097/md.0000000000033135
Abstract: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder. The pathogenesis of IBS has not yet been fully elucidated, and the relationship between human leukocyte antigen (HLA) class I molecules and IBS is… read more here.
Keywords: ibs; hla hla; hla; control ... See more keywords