Karyomapping in preimplantation genetic testing for β-thalassemia combined with HLA matching: a systematic summary
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-019-01595-7
Abstract: To investigate the validity, accuracy, and clinical outcomes of Karyomapping in preimplantation genetic testing (PGT) for β-thalassemia combined with human leukocyte antigen (HLA) matching. A total of 128 cycles from January 2014 to December 2017… read more here.
Keywords: genetic testing; karyomapping preimplantation; hla; thalassemia combined ... See more keywords
P114 Does HLA-DR matching prevent formation of de novo anti-donor HLA-DQ antibodies?
Sign Up to like & getrecommendations! Published in 2018 at "Human Immunology"
DOI: 10.1016/j.humimm.2018.07.172
Abstract: Aim Donor specific antibodies (DSA) directed to mismatched HLA-DQB antigens are the most prevalent DSA after transplantation. Such DSA have been implicated in the pathogenesis of chronic antibody mediated rejection and graft loss. Currently, patients… read more here.
Keywords: dsa; hla antibodies; hla; hla matching ... See more keywords
Time to Move on: HLA Matching Should Be Reconsidered in Modern Deceased Donor Kidney Allocation
Sign Up to like & getrecommendations! Published in 2022 at "Transplantation Direct"
DOI: 10.1097/txd.0000000000001295
Abstract: Background. HLA matching has been the cornerstone of deceased donor kidney allocation policies worldwide but can lead to racial inequity. Although HLA matching has been shown to improve clinical outcomes, the long-term impacts of nonallogenic… read more here.
Keywords: deceased donor; time; hla; hla matching ... See more keywords
Patient age and donor HLA matching can stratify allogeneic hematopoietic cell transplantation patients into prognostic groups
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Haematology"
DOI: 10.1111/ejh.13850
Abstract: Mixed results surround the accuracy of commonly used prognostic risk scores to predict overall survival (OS) and non‐relapse mortality (NRM) in allogeneic hematopoietic stem cell transplant (allo‐HCT) recipients. We hypothesize that a simple prognostic score… read more here.
Keywords: cell; donor hla; allogeneic hematopoietic; hla matching ... See more keywords
BSHI guideline: HLA matching and donor selection for haematopoietic progenitor cell transplantation
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Immunogenetics"
DOI: 10.1111/iji.12527
Abstract: A review of the British Society for Histocompatibility and Immunogenetics (BSHI) Guideline ‘HLA matching and donor selection for haematopoietic progenitor cell transplantation’ published in 2016 was undertaken by a BSHI appointed writing committee. Literature searches… read more here.
Keywords: matching donor; bshi guideline; selection haematopoietic; donor selection ... See more keywords
The First Asian, Single-Center Experience of Blastocyst Preimplantation Genetic Diagnosis with HLA Matching in Thailand for the Prevention of Thalassemia and Subsequent Curative Hematopoietic Stem Cell Transplantation of Twelve Affected Siblings
Sign Up to like & getrecommendations! Published in 2020 at "BioMed Research International"
DOI: 10.1155/2020/5292090
Abstract: Results In 221 cycles from 138 patients (104 cycles requiring HLA matching), 90.5% had embryo(s) biopsied for genetic testing. There were 119 embryo transfers for thalassemia (76) and thalassemia-HLA cases (43), respectively, resulting in overall… read more here.
Keywords: pgd hla; affected siblings; thalassemia; hla ... See more keywords
Impact of Allele-Level HLA-Matching on Outcomes after Double Cord Blood Transplantation in Adults with Malignancies.
Sign Up to like & getrecommendations! Published in 2023 at "Blood advances"
DOI: 10.1182/bloodadvances.2022009251
Abstract: In single unrelated cord blood transplantation (UCBT), an increasing number of HLA allele mismatches (MM) has been associated with inferior overall survival (OS) attributed to higher transplant-related mortali-ty (TRM). Previous studies on the role of… read more here.
Keywords: allele level; hla; level hla; hla matching ... See more keywords
Can PIRCHE-II Matching Outmatch Traditional HLA Matching?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.631246
Abstract: We analyzed in a cohort of 68,606 first deceased donor kidney transplantations reported to the Collaborative Transplant Study whether an epitope-based matching of donor-recipient pairs using the Predicted Indirectly ReCognizable HLA Epitopes algorithm (PIRCHE-II) is… read more here.
Keywords: traditional hla; pirche; pirche scores; hla ... See more keywords