HLAB: learning the BiLSTM features from the ProtBert-encoded proteins for the class I HLA-peptide binding prediction
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac173
Abstract: Abstract Human Leukocyte Antigen (HLA) is a type of molecule residing on the surfaces of most human cells and exerts an essential role in the immune system responding to the invasive items. The T cell… read more here.
Keywords: class hla; hlab; hla; hla peptide ... See more keywords
Development of antidrug antibodies against adalimumab maps to variation within the HLA-DR peptide-binding groove
Sign Up to like & getrecommendations! Published in 2023 at "JCI Insight"
DOI: 10.1172/jci.insight.156643
Abstract: Targeted biologic therapies can elicit an undesirable host immune response characterized by the development of antidrug antibodies (ADA), an important cause of treatment failure. The most widely used biologic across immune-mediated diseases is adalimumab, a… read more here.
Keywords: antidrug antibodies; development antidrug; development; hla peptide ... See more keywords