Characterization of Viral Epitopes and the HLA Restriction That Govern Anti-Adenoviral Response to Viral Specific T-Lymphocyte Therapy in a Pediatric Cohort
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DOI: 10.1016/j.bbmt.2019.12.340
Abstract: Introduction Adenoviral (AdV) infections are common after HSCT and are a major cause of complications. Antiviral medications are frequently ineffective and toxic. At CCHMC, viral specific T cells (VST) from 3rd party donors are generated… read more here.
Keywords: adv; response; product; hla restriction ... See more keywords
Therapeutic advantages provided by banked virus-specific T-cells of defined HLA-restriction
Sign Up to like & getrecommendations! Published in 2019 at "Bone Marrow Transplantation"
DOI: 10.1038/s41409-019-0614-1
Abstract: We have developed banks of EBV and CMV-specific T-cell lines generated from healthy seropositive third party donors and characterized them as to their HLA type, virus specificity, lack of alloreactivity, and HLA restriction. We here… read more here.
Keywords: specific cells; third party; therapeutic advantages; virus specific ... See more keywords