HLA‐HD: An accurate HLA typing algorithm for next‐generation sequencing data
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DOI: 10.1002/humu.23230
Abstract: The accurate typing of human leukocyte antigen (HLA) alleles is critical for a variety of medical applications, such as genomic studies of multifactorial diseases, including immune system and inflammation‐related disorders, and donor selection in organ… read more here.
Keywords: hla alleles; accurate; hla typing; hla ... See more keywords
HLApers: HLA Typing and Quantification of Expression with Personalized Index.
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DOI: 10.1007/978-1-0716-0327-7_7
Abstract: The plethora of RNA-seq data which have been generated in the recent years constitutes an attractive resource to investigate HLA variation and its relationship with normal and disease phenotypes, such as cancer. However, next generation… read more here.
Keywords: typing quantification; hla typing; expression; quantification expression ... See more keywords
HLA testing in the molecular diagnostic laboratory
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DOI: 10.1007/s00428-018-2501-3
Abstract: The human leukocyte antigen (HLA) system is a highly polymorphic family of genes involved in immunity and responsible for identifying self versus non-self. HLA typing is essential for solid organ and bone marrow transplantation as… read more here.
Keywords: diagnostic laboratory; hla typing; hla; testing molecular ... See more keywords
HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample
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DOI: 10.1016/j.bbi.2018.03.001
Abstract: BACKGROUND The infections Toxoplasma gondii (T. gondii), cytomegalovirus, and Herpes Simplex Virus Type 1 (HSV1) are common persistent infections that have been associated with schizophrenia and bipolar disorder. The major histocompatibility complex (MHC, termed HLA… read more here.
Keywords: schizophrenia bipolar; genome wide; hla typing; hla ... See more keywords
P097 An HLA typing assay using the illumina NGS system allows for the detection of poorly amplified HLA alleles, virtually eliminating allele dropout
Sign Up to like & getrecommendations! Published in 2017 at "Human Immunology"
DOI: 10.1016/j.humimm.2017.06.157
Abstract: Aim DNA sequencing has long been the gold standard for HLA typing, offering the ability to interrogate each base pair of a targeted region. Sanger sequencing-based typing assays are known to suffer from allele dropout,… read more here.
Keywords: detection; poorly amplified; hla typing; typing assay ... See more keywords
P201 Erroneous HLA-B allele typing by sequencing-based typing method that utilizes combinations of Sanger sequencing and rSSO typing
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DOI: 10.1016/j.humimm.2017.06.261
Abstract: Allele-level HLA matching reduces graft-versus-host disease and improves overall patient survival after hematopoietic stem cell transplantation (HSCT). Sanger sequencing has been the gold standard for allele-level HLA typing since 1996. The typing strategy typically employs… read more here.
Keywords: rsso typing; erroneous hla; hla typing; hla ... See more keywords
P226 Investigation of loss of alleles in next generation sequencing HLA typing
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DOI: 10.1016/j.humimm.2017.06.286
Abstract: The HLA typing laboratory of the Hellenic Cord Blood Bank, has been using NGS technology for the routine typing of the Cord Blood Units and the paired mother samples since 2015. In November 2016, a… read more here.
Keywords: loci; p226 investigation; hla; hla typing ... See more keywords
P252 Conceptualization to implementation in 90 days of full gene HLA typing using mia fora HLA flex kits at Jeevan stem cell foundation, India
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DOI: 10.1016/j.humimm.2017.06.312
Abstract: Aim Next Generation Sequencing (NGS) is rapidly becoming the method of choice for HLA typing for Hematopoietic Stem Cell Transplantation. Jeevan Stem Cell Foundation, Chennai, India validated the full gene HLA typing using Immucor’s MIA… read more here.
Keywords: stem cell; mia fora; hla; hla typing ... See more keywords
P258 Evaluation of high-resolution HLA typing of Japanese samples using NXType™ NGS HLA typing kit
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DOI: 10.1016/j.humimm.2017.06.318
Abstract: Aim The human MHC region has been shown to be associated with a wide range of diseases.The recent advancement in the next generation sequencing (NGS) technology has definitely helped in increasing the resolution (up to… read more here.
Keywords: resolution; typing kit; ngs hla; hla typing ... See more keywords
P034 When bone marrow transplant recipients become deceased organ donors – A case report
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DOI: 10.1016/j.humimm.2018.07.092
Abstract: Blood samples for ABO and HLA typing were received from the OPO on a potential deceased donor. The donor medical records indicated AMS due to hemorrhagic stroke, no significant PMH and no recent transfusions. ABO… read more here.
Keywords: transplant; case; donor; hla typing ... See more keywords
P088 Effect of leukoreduction of transfused blood products on deceased donor hla typing
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DOI: 10.1016/j.humimm.2018.07.147
Abstract: Aim Deceased donor HLA typing is predicated on the assumption that the blood sample contains only DNA from the organ donor. Prior to procurement, most organ donors receive at least one unit of red blood… read more here.
Keywords: hla; hla typing; transfusion; blood ... See more keywords