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   Articles with "hld" as a keyword



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Metabolic profiling of copper‐laden hepatolenticular degeneration model rats and the interventional effects of Gandou decoction using UPLC‐Q‐TOF/MS

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recommendations! Published in 2019 at "Journal of Pharmaceutical and Biomedical Analysis"

DOI: 10.1016/j.jpba.2018.10.041

Abstract: Graphical abstract Figure. No Caption available. HighlightsCopper‐laden rat model was established to study the therapeutic effect of Gandou decoction (GDD) on hepatolenticular degeneration (HLD).A UPLC‐Q‐TOF/MS‐based serum metabolomic approach was used to further provide a global… read more here.

Keywords: hepatolenticular degeneration; metabolism; hld; copper ... See more keywords
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Sub-Inhibitory Concentrations of Oxacillin, but Not Clindamycin, Linezolid, or Tigecycline, Decrease Staphylococcal Phenol-Soluble Modulin Expression in Community-Acquired Methicillin-Resistant Staphylococcus aureus

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recommendations! Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.00808-21

Abstract: Staphylococcal toxins play an important role in the physiopathology of staphylococcal infections. Subinhibitory concentrations (sub-MIC) of antibiotics modulate in vitro toxins expression in S. aureus: clindamycin (CLI) and linezolid (LIN) display an anti-toxin effect on… read more here.

Keywords: effect; hld; sub mic; expression ... See more keywords
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Management of Hypertension and Hyperlipidemia in Youth with T2D

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recommendations! Published in 2018 at "Diabetes"

DOI: 10.2337/db18-1342-p

Abstract: Introduction: Youth with T2D are at risk for additional cardiovascular (CVD) diseases such as hypertension (HT) and hyperlipidemia (HLD). We examined healthcare provider (HCP) self-reported practices regarding management and treatment of HT and HLD in… read more here.

Keywords: treatment; hld; youth t2d; inc ... See more keywords
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Protective Mechanism of Gandou Decoction in a Copper-Laden Hepatolenticular Degeneration Model: In Vitro Pharmacology and Cell Metabolomics

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recommendations! Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.848897

Abstract: Gandou decoction (GDD) is a classic prescription for the treatment of hepatolenticular degeneration (HLD) in China; however, the liver-protecting mechanism of this prescription needs further evaluation. In the present study, we explored the protective mechanisms… read more here.

Keywords: copper; pharmacology; hld; model ... See more keywords