Role of lactoferrin and its receptors on biliary epithelium
Sign Up to like & getrecommendations! Published in 2018 at "BioMetals"
DOI: 10.1007/s10534-018-0094-6
Abstract: Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids. This protein has antimicrobial,… read more here.
Keywords: lactoferrin receptors; role lactoferrin; biliary epithelium; role ... See more keywords
Structural transition of lactoferrin upon interaction with estradiol as revealed by spectroscopic techniques: a molten globule state investigation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-018-1409-9
Abstract: Proteins have numerous physiological functions in the body. Their most important property is serving as depot carriers and as target molecules for many drugs. Three-dimensional fluorescence spectroscopy, zeta potential analysis, resonance light scattering (RLS), thermodynamic… read more here.
Keywords: estradiol revealed; estradiol; hlf; globule state ... See more keywords
Downregulation of the Circadian Rhythm Regulator HLF Promotes Multiple-Organ Distant Metastases in Non-Small Cell Lung Cancer through PPAR/NF-κB Signaling.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer letters"
DOI: 10.1016/j.canlet.2020.04.007
Abstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death due to its early recurrence and widespread metastatic potential. Accumulating studies have reported that dysregulation of circadian rhythms-associated regulators is implicated in the… read more here.
Keywords: ppar; nsclc; non small; cancer ... See more keywords
Hinge-Deficient IgG1 Fc Fusion: Application to Human Lactoferrin.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00221
Abstract: Fusion of therapeutic proteins with the antibody Fc domain is a strategy widely applied to increase protein half-life in plasma. In our previous study, we generated a recombinant human lactoferrin (hLF)-immunoglobulin G1 Fc fusion protein… read more here.
Keywords: hinge; ch2 ch3; hlf; fusion ... See more keywords
Triple-mutant AML: too clever by HLF?
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood.2019001533
Abstract: In this issue of Blood, Garg et al report on their investigation of the molecular interaction between mutations affecting DNMT3A and NPM1, and internal tandem duplications (ITDs) of FLT3 in acute myeloid leukemia (AML). They… read more here.
Keywords: aml clever; triple mutant; hlf; aml ... See more keywords
Comprehensive chromosomal aberrations in a case of a patient with TCF3-HLF-positive BCP-ALL
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medical Genomics"
DOI: 10.1186/s12920-020-0709-y
Abstract: The use of high-throughput analytical techniques has enabled the description of acute lymphoblastic leukaemia (ALL) subtypes. The TCF3-HLF translocation is a very rare rearrangement in ALL that is associated with an extremely poor prognosis. The… read more here.
Keywords: tcf3 hlf; case; hlf positive; hlf ... See more keywords
Dysregulation of MicroRNAs in Hypertrophy and Ossification of Ligamentum Flavum: New Advances, Challenges, and Potential Directions
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2021.641575
Abstract: Pathological changes in the ligamentum flavum (LF) can be defined as a process of chronic progressive aberrations in the nature and structure of ligamentous tissues characterized by increased thickness, reduced elasticity, local calcification, or aggravated… read more here.
Keywords: ossification ligamentum; ligamentum flavum; hypertrophy; ossification ... See more keywords