Articles with "hlh" as a keyword



Hemophagocytic Lymphohistiocytosis in Cutaneous T-Cell Lymphoma

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Published in 2018 at "JAMA Dermatology"

DOI: 10.1001/jamadermatol.2018.1264

Abstract: Importance Hemophagocytic lymphohistiocytosis (HLH) has been reported as a serious complication of cutaneous T-cell lymphoma (CTCL). Despite available diagnostic guidelines, it remains a diagnostic and therapeutic challenge in this patient population. Objectives To examine the… read more here.

Keywords: cutaneous cell; hemophagocytic lymphohistiocytosis; cell; hlh ... See more keywords

High prevalence of osteonecrosis among the hemophagocytic lymphohistiocytosis population: Single institution 10‐year retrospective data review

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Published in 2017 at "American Journal of Hematology"

DOI: 10.1002/ajh.24828

Abstract: To the Editor: Hemophagocytic lymphohistiocytosis (HLH) is a rare disorder that is characterized by overactive natural-killer and cytotoxic T cells that improperly trigger macrophages and subsequently leads to hemophagocytosis in bone marrow, spleen, liver, and… read more here.

Keywords: osteonecrosis; secondary hlh; diagnosis; prevalence ... See more keywords

Establishment and characterization of a novel Hodgkin lymphoma cell line, AM‐HLH, carrying the Epstein‐Barr virus genome integrated into the host chromosome

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Published in 2017 at "Hematological Oncology"

DOI: 10.1002/hon.2369

Abstract: We describe the establishment and characterization of a cell line, AM‐HLH, obtained from a patient with Epstein‐Barr virus–positive (EBV+) nodular sclerosis–type Hodgkin lymphoma (HL). The cells were positive for CD2 and CD30 and negative for… read more here.

Keywords: establishment characterization; cell line; chromosome; hlh ... See more keywords

Secondary hemophagocytic lymphohistiocytosis associated with adjuvant pembrolizumab therapy in a young patient with triple-negative breast cancer: a case report with literature review

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Published in 2025 at "Archives of Gynecology and Obstetrics"

DOI: 10.1007/s00404-025-08078-4

Abstract: Secondary hemophagocytic lymphohistiocytosis (HLH) associated with pembrolizumab is a rare immune-related adverse event (irAE). It features a potential life-threatening status including fever and a hyperinflammatory reaction caused by natural killer cells, CD8 + cytotoxic T cells, and… read more here.

Keywords: pembrolizumab therapy; breast cancer; therapy; hlh ... See more keywords

Persistent fever in a pediatric renal transplant patient: Answers

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Published in 2018 at "Pediatric Nephrology"

DOI: 10.1007/s00467-018-4130-0

Abstract: Bone marrow biopsy showed presence of intracellular yeast forms along with rare histiocytes showing hemophagocytosis. Histoplasma serum Ag was positive and fungal blood and bone marrow cultures grew H. capsulatum. MRI of the brain with… read more here.

Keywords: cmv; histoplasma serum; bone marrow; therapy ... See more keywords

A Case of Chronic Lymphocytic Leukemia Complicated by Hemophagocytic Lymphohistiocytosis: Identifying the Aberrant Immune Response

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Published in 2022 at "Journal of General Internal Medicine"

DOI: 10.1007/s11606-022-07395-7

Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening hyperinflammatory syndrome that may complicate hematologic malignancies. HLH and malignancies have common clinical features, and HLH diagnostic criteria (HLH-2004/Hscore) were not validated in this specific population. We describe a… read more here.

Keywords: hlh; chronic lymphocytic; case; hemophagocytic lymphohistiocytosis ... See more keywords

Correspondence to: hemophagocytic lymphohistiocytosis after SARS-CoV-2 vaccination

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Published in 2022 at "Infection"

DOI: 10.1007/s15010-022-01820-z

Abstract: We thank Mungmunpuntipantip and colleagues for their interest in our recently published case of a young adult female developing hemophagocytic lymphohistiocytosis (HLH) after BionTech mRNA SARS-CoV-2 vaccine [1]. In their correspondence, the authors ask about… read more here.

Keywords: vaccination; correspondence; hlh; history ... See more keywords

A simple clinical tool for effective screening of haemophagocytic lymphohistiocytosis in dengue

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Published in 2025 at "Infection"

DOI: 10.1007/s15010-025-02542-8

Abstract: Haemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening disorder. Dengue fever is a common trigger for HLH in the tropics. We aimed to develop a simplified clinical tool to detect HLH in dengue patients. A cross-sectional… read more here.

Keywords: dengue; tool; clinical tool; haemophagocytic lymphohistiocytosis ... See more keywords
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Fatal COVID-19 infections: Is NK cell dysfunction a link with autoimmune HLH?

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Published in 2020 at "Autoimmunity Reviews"

DOI: 10.1016/j.autrev.2020.102561

Abstract: Shoenfeld [1] postulates that in COVID-19 infected patients a clinical constellation of cytokine storm, respiratory failure and eventually death is reminiscent of a “hyperferritinemic syndrome” a condition that resembles a hemophagocytic lymphohistiocytosis (HLH)-like syndrome. One… read more here.

Keywords: ivig; infection; covid; cytotoxicity ... See more keywords

Thinking Beyond HLH: Clinical Features of Patients with Concurrent Presentation of Hemophagocytic Lymphohistiocytosis and Thrombotic Microangiopathy

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Published in 2020 at "Biology of Blood and Marrow Transplantation"

DOI: 10.1016/j.bbmt.2019.12.080

Abstract: Introduction Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune system activation largely driven by high levels of interferon gamma. The clinical HLH presentation can have considerable overlap with other inflammatory conditions. We present a… read more here.

Keywords: presentation; hemophagocytic lymphohistiocytosis; tma; thrombotic microangiopathy ... See more keywords
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Hemophagocytic Lymphohistiocytosis, a Rare Presentation in Lupus Nephritis

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Published in 2021 at "Kidney International Reports"

DOI: 10.1016/j.ekir.2020.11.036

Abstract: INTRODUCTION H emophagocytic lymphohistiocytosis (HLH) is a rare immune disorder that is life threatening if not promptly diagnosed and treated. Its identification, however, remains a diagnostic challenge for clinicians, given the large overlap in presenting… read more here.

Keywords: lymphohistiocytosis; hemophagocytosis; disease; hemophagocytic lymphohistiocytosis ... See more keywords