Busulfan-based reduced toxicity conditioning regimen used in hematopoietic stem cell transplantation in HLH patients results in sustained donor chimerism
Sign Up to like & getrecommendations! Published in 2021 at "Pediatric Hematology and Oncology"
DOI: 10.1080/08880018.2020.1868638
Abstract: Hemophagocytic lymphohistiocytosis (HLH) is a severe systemic inflammatory syndrome characterized by excessive inflammation and an ineffective immune response. This syndrome, often driven by a genetic abnormality, can ultimately be fatal if unsuccessfully controlled. Allogeneic hematopoietic… read more here.
Keywords: busulfan based; hlh patients; conditioning regimen; hematopoietic stem ... See more keywords
Hemophagocytic Lymphohistiocytosis in Langerhans Cell Histiocytosis: A Case Series and Literature Review
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DOI: 10.1097/mph.0000000000002212
Abstract: Langerhans cell histiocytosis (LCH) is characterized pathologically by langerin-positive (CD207+) dendritic cell proliferation and is considered by some as a myeloid neoplastic disorder. Hemophagocytic lymphohistiocytosis (HLH) is associated with immune dysregulation characterized by the accumulation… read more here.
Keywords: histiocytosis; hlh patients; langerhans cell; lch hlh ... See more keywords
Haemophagocytic lymphohistiocytosis (HLH) in patients with large B-cell lymphoma treated with standard of care (SOC) axicabtagene ciloleucel (Axi-cel).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.8057
Abstract: 8057Background: HLH is a rare but serious complication of chimeric antigen receptor (CAR) T cell therapy, characterized by severe immune activation, and immune mediated multi-organ failure. Diagnos... read more here.
Keywords: lymphohistiocytosis hlh; hlh patients; patients large; haemophagocytic lymphohistiocytosis ... See more keywords
Haemophagocytic lymphohistiocytosis in human immunodeficiency virus: a systematic review of literature.
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DOI: 10.5582/ddt.2020.03069
Abstract: Diagnosis and management of hemophagocytic lymphohistiocytosis (HLH) in patients with human immunodeficiency virus (HIV) infection are scarcely described in the published literature. The aim of this systematic review was to delineate the triggers of HLH… read more here.
Keywords: human immunodeficiency; literature; hlh patients; review ... See more keywords