Effects of alcohol-induced increase in CYP2E1 content in human liver microsomes on the activity and cooperativity of CYP3A4.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108677
Abstract: We investigate the effect of the alcohol-induced increase in the content of CYP2E1 in human liver microsomes (HLM) on the function of CYP3A4. Membrane incorporation of the purified CYP2E1 into HLM considerably increases the rate… read more here.
Keywords: induced increase; cyp2e1; hlm; alcohol induced ... See more keywords
Inter-rater reliability of the Johns Hopkins Highest Level of Mobility Scale (JH-HLM) in the intensive care unit.
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian journal of physical therapy"
DOI: 10.1016/j.bjpt.2020.07.010
Abstract: BACKGROUND The Johns Hopkins Highest Level of Mobility (JH-HLM) scale is used to document the observed mobility of hospitalized patients, including those patients in the intensive care unit (ICU) setting. OBJECTIVE To evaluate the inter-rater… read more here.
Keywords: rater reliability; rater; inter rater; hlm ... See more keywords
In-loop oxygen reduction in HLM thermal-hydraulic facility NACIE-UP
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Nuclear Energy"
DOI: 10.1016/j.pnucene.2018.01.006
Abstract: Abstract NACIE-UP loop located at the ENEA Brasimone Research Centre is an experimental thermal-hydraulic facility working with liquid lead-bismuth eutectic (LBE). The facility was designed and constructed with the purpose to support the research activity… read more here.
Keywords: oxygen; reduction; thermal hydraulic; facility ... See more keywords
GEN-IV LFR development: Status & perspectives
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DOI: 10.1016/j.pnucene.2018.02.005
Abstract: Abstract Since Lead-cooled Fast Reactors (LFR) have been conceptualized in the frame of Generation IV International Forum (GIF), great interest has focused on the development and testing of new technologies related to Heavy Liquid Metal… read more here.
Keywords: liquid metal; development status; lfr development; hlm ... See more keywords
From Steps to Mobility Levels: Validating a Consumer-Grade Activity Monitor for Automated Recording of Patient Mobility in Hospitals
Sign Up to like & getrecommendations! Published in 2024 at "Applied Clinical Informatics"
DOI: 10.1055/a-2576-1505
Abstract: Abstract Background Patient mobility during hospitalization is essential for high-quality healthcare as mobility is linked to physical function and quality of life. The Johns Hopkins Highest Level of Mobility (JH-HLM) scale is a validated method… read more here.
Keywords: activity monitor; hlm; mobility; hlm scores ... See more keywords
Bernard J. Miller: MD, ScD. (Hon), FACS: Lifelong Surgeon-Scientist and Critical Contributor to the Gibbon Heart-Lung Machine.
Sign Up to like & getrecommendations! Published in 2021 at "ASAIO journal"
DOI: 10.1097/mat.0000000000001227
Abstract: Bernard J. Miller, MD, ScD. (Hon), FACS, is known as a critical contributor for his work in the John H. Gibbon, MD, laboratory for his work on the heart-lung machine (HLM). In this setting, Dr.… read more here.
Keywords: scd hon; miller; heart; bernard miller ... See more keywords
Evaluation of the Disconnect between Hepatocyte and Microsome Intrinsic Clearance and In Vitro In Vivo Extrapolation Performance
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DOI: 10.1124/dmd.120.000131
Abstract: The use of in vitro in vivo extrapolation (IVIVE) from human hepatocyte (HH) and human liver microsome (HLM) stability assays is a widely accepted predictive methodology for human metabolic clearance (CLmet). However, a systematic underprediction… read more here.
Keywords: vitro vivo; hlm; clearance; vivo extrapolation ... See more keywords