Articles with "hlms matrix" as a keyword



Ultra‐Fast UPLC‐MS/MS Method for the Ripretinib Quantification in the HLMs Matrix With Metabolic Stability Assessment: In‐Silico Study for Toxic Alerts and the Metabolic Lability

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Published in 2025 at "Archiv der Pharmazie"

DOI: 10.1002/ardp.70130

Abstract: Ripretinib (QINLOCK) is a broad‐spectrum, orally‐administered, switch‐controlled kinase inhibitor that got FDA approval in May 2020 for the treatment of advanced gastrointestinal stromal tumors (GIST) in adult patients who have formerly had treatment with three or… read more here.

Keywords: hlms matrix; stability; metabolic stability; silico ... See more keywords