Protein synthesis, autophagy, and regeneration-related signaling in fast/slow muscles in two mammalian models of disuse
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DOI: 10.1139/cjz-2024-0061
Abstract: Whether regulation of protein synthesis, autophagy, and regeneration are involved in slow/fast muscles in two disuse models (hindlimb unloading Sprague-Dawley rats ( Rattus norvegicus domestica (Berkenhout, 1769))) (HLU) and hibernating ground squirrels ( Spermophilus dauricus… read more here.
Keywords: hib; synthesis autophagy; autophagy regeneration; hlu ... See more keywords
Combined Effects of Low-Dose Proton Radiation and Simulated Microgravity on the Mouse Retina and the Hematopoietic System.
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DOI: 10.1667/rr15219.1
Abstract: The purpose of the current study was to characterize the effects of simulated microgravity and radiation-induced changes in retina and retinal vasculature, and to assess the accompanying early changes in immune cells and hematological parameters.… read more here.
Keywords: low dose; compared controls; simulated microgravity; hlu ... See more keywords
Hindlimb unloading in C57BL/6J mice induces bone loss at thermoneutrality without change in osteocyte and lacuno-canalicular network.
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DOI: 10.2139/ssrn.4232740
Abstract: Impaired mechanical stimuli during hindlimb unloading (HLU) are believed to exacerbate osteocyte paracrine regulation of osteoclasts. We hypothesized that bone loss and deterioration of the osteocyte lacuno-canalicular network are attenuated in HLU mice housed at… read more here.
Keywords: bone loss; lacuno canalicular; hlu; canalicular network ... See more keywords