Articles with "hlx" as a keyword



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Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation

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Published in 2017 at "Nature Communications"

DOI: 10.1038/s41467-017-00098-2

Abstract: Browning of subcutaneous white fat (iWAT) involves several reprograming events, but the underlying mechanisms are incompletely understood. Here we show that the transcription factor Hlx is selectively expressed in brown adipose tissue (BAT) and iWAT,… read more here.

Keywords: hlx; factor hlx; transcription factor; fat ... See more keywords
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Abstract 4764: The therapeutic potential of lnc-HLX-2-7 in group 3 medulloblastomas in children

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4764

Abstract: Medulloblastoma (MB) is an aggressive brain tumor that predominantly affects children. Recent high-throughput sequencing studies suggest that the non-coding RNA genome, in particular long non-coding RNAs (lncRNAs), contributes to MB formation and tumor progression. Here… read more here.

Keywords: therapeutic potential; hlx; group; lnc hlx ... See more keywords
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Methotrexate-Induced Nephrotoxicity in Rats: Protective Effect of Mistletoe (Viscum album L.) Extract

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Published in 2017 at "Complementary Medicine Research"

DOI: 10.1159/000468984

Abstract: Background: The protective effect of mistletoe extract (Helixor®, HLX) against methotrexate (MTX)-induced acute oxidative stress and nephrotoxicity in rats was evaluated by histological and biochemical methods as well as the comet assay. Material and Methods:… read more here.

Keywords: nephrotoxicity rats; group; hlx; mtx induced ... See more keywords