Articles with "hm97662" as a keyword



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Abstract 6267: A novel and potent EZH1/2 dual inhibitor, HM97662 demonstrates antitumor activity in T-cell lymphoma

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-6267

Abstract: Chromatin remodeling is a crucial process for transcriptional regulation, of which dysregulation is often observed in various human cancers. The enhancer of zeste homology 2 (EZH2) and its homolog EZH1 are catalytic subunits of polycomb… read more here.

Keywords: cell; cell lymphoma; hm97662; ezh1 ... See more keywords