TSH inhibits eNOS expression in HMEC-1 cells through the TSHR/PI3K/AKT signaling pathway.
Sign Up to like & getrecommendations! Published in 2019 at "Annales d'endocrinologie"
DOI: 10.1016/j.ando.2019.06.007
Abstract: OBJECTIVE To investigate the effects of thyroid-stimulating hormone (TSH) on the expression of endothelial nitric oxide synthase (eNOS) in human microvascular endothelial cells (HMEC-1) and explore the potential mechanism. MATERIALS AND METHODS Expression of thyroid-stimulating… read more here.
Keywords: expression; hmec; hmec cells; signaling pathway ... See more keywords
Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Aging"
DOI: 10.18632/aging.203648
Abstract: Renal hypoxia is associated with persisting peritubular capillary rarefaction in progression of chronic kidney disease (CKD), and this phenomenon mainly resulted from the dysregulated angiogenesis. Rab7 is known to be involved in renal hypoxia. However,… read more here.
Keywords: knockdown rab7; angiogenesis; renal hypoxia; hypoxia ... See more keywords