hMENA is a key regulator in endothelin-1/β-arrestin1–induced invadopodial function and metastatic process
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DOI: 10.1073/pnas.1715998115
Abstract: Significance Discovering new targets and novel determinants of metastatic spread is an unmet need in ovarian cancer, which is plagued by high rates of recurrence. Endothelin-1 receptors (ET-1R), belonging to the G-protein–coupled receptor family, represent… read more here.
Keywords: ovarian cancer; hmena; arrestin1; function ... See more keywords