Triplex forming oligonucleotides targeted to hmga1 selectively inhibit its expression and induce apoptosis in human cervical cancer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2016.1160257
Abstract: High-mobility group A1 (HMGA1) is a non-histone chromosomal protein, which is known as ‘architectural’ transcription factor that facilitates the assembly of ‘enhanceosome.’ Because of its elevated expression in a number of human malignancies, with barely… read more here.
Keywords: forming oligonucleotides; triplex forming; expression; cancer ... See more keywords
High Mobility Group A 1 Expression as a Poor Prognostic Marker Associated with Tumor Invasiveness in Gastric Cancer
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DOI: 10.3390/life12050709
Abstract: The prognosis of advanced gastric cancer remains poor. Overexpression of high mobility group A 1 (HMGA1) in breast cancer and neuroblastoma indicates a poor prognosis. However, the relationship between HMGA1 expression and gastric cancer development… read more here.
Keywords: mobility group; hmga1 expression; expression; gastric cancer ... See more keywords