HMGB proteins involved in TOR signaling as general regulators of cell growth by controlling ribosome biogenesis
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DOI: 10.1007/s00294-018-0842-8
Abstract: The number of ribosomes and their activity need to be highly regulated because their function is crucial for the cell. Ribosome biogenesis is necessary for cell growth and proliferation in accordance with nutrient availability and… read more here.
Keywords: ribosome biogenesis; cell growth; tor; hmgb proteins ... See more keywords
Targeting Chromosomal Architectural HMGB Proteins Could Be the Next Frontier in Cancer Therapy
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DOI: 10.1158/0008-5472.can-19-3066
Abstract: Chromatin-associated architectural proteins are part of a fundamental support system for cellular DNA-dependent processes and can maintain/modulate the efficiency of DNA replication, transcription, and DNA repair. Interestingly, prognostic outcomes of many cancer types have been… read more here.
Keywords: dna; cancer; hmgb proteins; etiology ... See more keywords