Sepsis-induced acute lung injury in young rats is relieved by calycosin through inactivating the HMGB1/MyD88/NF-κB pathway and NLRP3 inflammasome.
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DOI: 10.1016/j.intimp.2021.107623
Abstract: PURPOSE Sepsis is the primary cause for children's death worldwide. Calycosin (CAL) is an astragalus extract with anti-inflammatory, antioxidant and anti-tumor functions. This study aims to probe the role of CAL in alleviating sepsis-induced acute… read more here.
Keywords: sepsis; young rats; lung; hmgb1 myd88 ... See more keywords