Crucial role of high-mobility group box 2 in mouse ovarian follicular development through estrogen receptor beta.
Sign Up to like & getrecommendations! Published in 2022 at "Histochemistry and cell biology"
DOI: 10.1007/s00418-022-02074-4
Abstract: High-mobility group box 2 (HMGB2) is a chromatin-associated protein that is an important regulator of gene transcription, recombination, and repair processes. The functional importance of HMGB2 has been reported in various organs, including the testis,… read more here.
Keywords: mouse; mobility group; role; hmgb2 ... See more keywords
HMGB2 is associated with pressure loading in chondrocytes of temporomandibular joint: In vitro and in vivo study.
Sign Up to like & getrecommendations! Published in 2019 at "Cytokine"
DOI: 10.1016/j.cyto.2019.154875
Abstract: High mobility group protein B2 (HMGB2) is an important protein attributed to tissue function and homeostasis in osteoarthritis (OA), however, its roles in the temporomandibular joint with mechanical pressure are unclear. This study investigated the… read more here.
Keywords: pressure loading; temporomandibular joint; study; hmgb2 ... See more keywords
HMGB2-induced calreticulin translocation required for immunogenic cell death and ferroptosis of cancer cells are controlled by the nuclear exporter XPO1
Sign Up to like & getrecommendations! Published in 2024 at "Communications Biology"
DOI: 10.1038/s42003-024-06930-y
Abstract: Cisplatin and oxaliplatin cause the secretion of high mobility group box 1 (HMGB1) protein from cancer cells, which is necessary for initiation of immunogenic cell death (ICD). Calreticulin (CRT) translocation from the endoplasmic reticulum to… read more here.
Keywords: cancer; cancer cells; hmgb2; cell death ... See more keywords
Bidirectional roles of extracellular and intracellular HMGB2 in the development of atherosclerosis
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.3876
Abstract: Rationale: HMGB family plays an important role in homeostasis of immunity and regulation of inflammation. However, the role of HMGB2 in atherosclerosis remains uncharacterized. The current study aimed to ascertain the relation of HMGB2 levels… read more here.
Keywords: mice; atherosclerosis; hmgb2; hmgb2 levels ... See more keywords
RBIO-13. Shift in Subcellular Expression and Increase in Immune Response Pathways After Radiation Suggests that HMGB2 is a Damage-Associated Molecular Pattern (DAMP) in Gliomas
Sign Up to like & getrecommendations! Published in 2025 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noaf201.1553
Abstract: While HMGB2 nuclear expression in gliomas is associated with enhanced cell proliferation, high HMGB2 expression in adult glioblastomas yielded better response to treatments with radiation+temozolomide and with viral vectors. Here we aimed to explore causes… read more here.
Keywords: radiation; response; culture; hmgb2 ... See more keywords
DLBCL-Derived HMGB2 Inhibits Macrophage Phagocytosis By up-Regulating TRIM65 to Promote NLRP3 Ubiquitination
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-206478
Abstract: Background： Diffuse large B-cell lymphoma (DLBCL), the predominant non-Hodgkin lymphoma type, exhibits significant clinical and biological heterogeneity. Despite favorable outcomes with R-CHOP therapy in most cases, approximately 30-40% of patients experience disease progression or relapse.… read more here.
Keywords: dlbcl; macrophage phagocytosis; hmgb2; cell ... See more keywords
Transcriptional Repression of High-Mobility Group Box 2 by p21 in Radiation-Induced Senescence
Sign Up to like & getrecommendations! Published in 2018 at "Molecules and Cells"
DOI: 10.14348/molcells.2018.2291
Abstract: High mobility group box 2 (HMGB2) is an abundant, chromatin-associated, non-histone protein involved in transcription, chromatin remodeling, and recombination. Recently, the HMGB2 gene was found to be significantly downregulated during senescence and shown to regulate… read more here.
Keywords: p21; radiation induced; hmgb2; box ... See more keywords
Structural Characteristics of High-Mobility Group Proteins HMGB1 and HMGB2 and Their Interaction with DNA
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043577
Abstract: Non-histone nuclear proteins HMGB1 and HMGB2 (High Mobility Group) are involved in many biological processes, such as replication, transcription, and repair. The HMGB1 and HMGB2 proteins consist of a short N-terminal region, two DNA-binding domains,… read more here.
Keywords: hmgb1 hmgb2; dna; mobility group; proteins hmgb1 ... See more keywords