Articles with "hmgb3" as a keyword



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CIRCULAR RNA CIRC_0099188 CONTRIBUTES TO LPS-INDUCED HPAEpiC CELL INJURY BY TARGETING THE MIR-1236-3P/HMGB3 AXIS

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Published in 2023 at "Shock"

DOI: 10.1097/shk.0000000000002100

Abstract: ABSTRACT Purpose: This study is designed to explore the role and mechanism of circ_0099188 in LPS-engendered HPAEpiC cells. Methods: Circ_0099188, microRNA-1236-3p (miR-1236-3p), and high mobility group box 3 (HMGB3) levels were measured using real-time quantitative… read more here.

Keywords: cell; hpaepic; hmgb3; circ 0099188 ... See more keywords

PVT1 inhibits miR-515-5p function and modulate HMGB3 to promote the growth of prostate cancer cells.

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Published in 2022 at "Andrology"

DOI: 10.1111/andr.13285

Abstract: AIM This study is performed to analyze the role of long non-coding RNA (lncRNA) plasmacytoma variant translocation 1 (PVT1) in prostate cancer (PCa). METHODS AND MATERIALS PVT1, miR-515-5p, and high mobility group B3 (HMGB3) mRNA… read more here.

Keywords: prostate cancer; hmgb3; expression; mir 515 ... See more keywords

HMGB3 Targeted by miR-145-5p Impacts Proliferation, Migration, Invasion, and Apoptosis of Breast Cancer Cells

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Published in 2022 at "Computational and Mathematical Methods in Medicine"

DOI: 10.1155/2022/1954099

Abstract: This study focused on the investigation into how HMGB3 works in breast cancer (BC) progression. Firstly, we analyzed the relationship between HMGB3 and BC patients through the TCGA database. We performed qRT-PCR for determining the… read more here.

Keywords: proliferation migration; hmgb3; migration invasion; breast cancer ... See more keywords
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HMGB3 promotes growth and migration in colorectal cancer by regulating WNT/β-catenin pathway

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Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0179741

Abstract: Colorectal cancer (CRC) is the third leading cause of cancer-related deaths and a major health problem. High mobility group box 3 (HMGB3), a member of the high-mobility group box (HMGB) family, was reported to be… read more here.

Keywords: colorectal cancer; catenin pathway; crc; cancer ... See more keywords

LINC00504 Promotes the Malignant Biological Behavior of Breast Cancer Cells by Upregulating HMGB3 via Decoying MicroRNA-876-3p

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Published in 2021 at "Cancer Management and Research"

DOI: 10.2147/cmar.s276290

Abstract: Purpose Long intergenic non-protein coding RNA 504 (LINC00504) is a long non-coding RNA that has an important regulatory role in a variety of human cancers. In this study, LINC00504 expression in breast cancer tissues and… read more here.

Keywords: hmgb3; cancer cells; linc00504; cancer ... See more keywords
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Circ-0001801 contributes to cell proliferation, migration, invasion and epithelial to mesenchymal transition (EMT) in glioblastoma by regulating miR-628-5p/HMGB3 axis.

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Published in 2019 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_201912_19791

Abstract: OBJECTIVE Glioblastoma (GBM) is a fast-growing type of central nervous system tumor with high invasiveness and recurrence. Circular RNA (circRNA) circ-0001801 (also named as circPCMTD1) was recognized as a novel biomarker in cancers. However, the… read more here.

Keywords: circ 0001801; gbm; mir 628; migration invasion ... See more keywords
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Expression, tumor immune infiltration, and prognostic impact of HMGs in gastric cancer

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.1056917

Abstract: Background In the past decade, considerable research efforts on gastric cancer (GC) have been expended, however, little advancement has been made owing to the lack of effective biomarkers and treatment options. Herein, we aimed to… read more here.

Keywords: hmgb3; immune infiltration; expression; hmgs ... See more keywords
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Abnormal expression of HMGB-3 is significantly associated with malignant transformation of hepatocytes

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Published in 2018 at "World Journal of Gastroenterology"

DOI: 10.3748/wjg.v24.i32.3650

Abstract: AIM To explore the relationship between dynamic expression of high mobility group box-3 (HMGB3) and malignant transformation of hepatocytes. METHODS Expression of HMGB family proteins were observed in rat hepatocarcinogenesis models induced with 2-acetylaminofluorene. Alterations… read more here.

Keywords: expression hmgb; malignant transformation; transformation hepatocytes; expression ... See more keywords
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MicroRNA-429 acts as a tumor suppressor in colorectal cancer by targeting high mobility group box 3

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Published in 2021 at "Oncology Letters"

DOI: 10.3892/ol.2021.12511

Abstract: Colorectal cancer (CRC) is one of the most common solid tumors worldwide and has an extremely poor prognosis. MicroRNA-429 (miR-429) has been reported to participate in the progression of CRC. However, the pathological mechanisms require… read more here.

Keywords: mir 429; colorectal cancer; expression; crc ... See more keywords