Anti‐HMGCR autoantibodies in self‐limiting statin‐induced myopathy
Sign Up to like & getrecommendations! Published in 2017 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13025
Abstract: Dear Editor, Since their introduction in the 1990s, statins have become one of the most commonly prescribed medications worldwide. By specifically inhibiting 3-hydroxy-3methylglutaryl-coenzyme A reductase (HMGCR), a key enzyme in the cholesterol synthesis pathway, they… read more here.
Keywords: anti hmgcr; hmgcr; statin induced; autoantibodies self ... See more keywords
Screening for Anti-HMGCR Antibodies in a Large Single Myositis Center Reveals Infrequent Exposure to Statins and Diversiform Presentation of the Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.866701
Abstract: Background The objective of this study is to assess the frequency of autoantibodies against 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase (HMGCR) in a single center myositis cohort and to analyze associations with statin exposure, clinical features, and outcome… read more here.
Keywords: rheumatology; hmgcr autoantibodies; myositis; hmgcr ... See more keywords