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Published in 2022 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2021.10.007
Abstract: Autoantibodies against 3‑hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and the signal recognition particle (SRP) are representative antibodies causing immune-mediated necrotizing myopathies (IMNM), called as anti-HMGCR and anti-SRP myopathies, respectively. Here, we analyzed the differences in routine blood test…
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Keywords:
anti;
hmgcr;
hmgcr myopathy;
anti srp ... See more keywords
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Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.2626
Abstract: Background: Anti-3-hydroxy-3-methylglutaryl-coenzime A reductase (HMGCR) myopathy is a new entity, which has been clearly associated to statin use, even if it can be diagnosed in patients without a history of exposure to statin or even…
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Keywords:
therapy;
none;
none declared;
hmgcr myopathy ... See more keywords
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Published in 2021 at "BMJ Case Reports"
DOI: 10.1136/bcr-2021-243728
Abstract: Immune-mediated necrotising myopathy is a subtype of idiopathic inflammatory myopathy characterised by muscle fibre necrosis without significant inflammatory infiltrate. Anti-3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) myopathy is seen in 6%–10% of idiopathic inflammatory myopathy and is…
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Keywords:
anti hmgcr;
hmgcr myopathy;
atypical presentation;
myopathy atypical ... See more keywords
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Published in 2022 at "Practical Neurology"
DOI: 10.1136/pn-2022-003589
Abstract: Anti-HMGCR (3-hydroxy-3-methylglutaryl coenzyme A reductase) myopathy is an immune-mediated necrotising myopathy. Atypical presentations hinder its recognition and its prompt treatment. We present two patients with atypical clinical or pathological features. A 45-year-old woman had an…
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Keywords:
recognition;
hmgcr myopathy;
hmgcr;
muscle ... See more keywords