Antibody Response to HML‐2 May Be Protective in Amyotrophic Lateral Sclerosis
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DOI: 10.1002/ana.26466
Abstract: Reactivation of HERV‐K(HML‐2) has been found in subsets of individuals with amyotrophic lateral sclerosis (ALS). This study examines the antibody response against HML‐2 in ALS and analyzes its clinical relevance. read more here.
Keywords: amyotrophic lateral; antibody response; hml; lateral sclerosis ... See more keywords
Limits to Transcriptional Silencing in Saccharomyces cerevisiae.
Sign Up to like & getrecommendations! Published in 2022 at "Genetics"
DOI: 10.1093/genetics/iyac180
Abstract: Mating-type switching in the budding yeast Saccharomyces cerevisiae relies on the Sir protein complex to silence HML and HMR, the two loci containing copies of the alleles of the mating type locus, MAT. Sir-based transcriptional… read more here.
Keywords: locus; hml; transcriptional silencing; gene ... See more keywords
HML-RF: Hybrid Multi-Label Random Forest
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DOI: 10.1109/access.2022.3154420
Abstract: Multi-label classification is the supervised learning problem in which an instance is associated with a set of labels. In this, labels are correlated, and hence label dependency information plays a vital role. Its always been… read more here.
Keywords: problem; hybrid multi; hml; multi label ... See more keywords
Evaluation of full-fatted and hydrolysate mealworm (Tenebrio molitor) larvae as a substitute for spray-dried plasma protein diet in weaning pigs.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of animal physiology and animal nutrition"
DOI: 10.1111/jpn.13763
Abstract: The goal of this experiment was to examine the effect of dietary inclusion of full-fatted mealworm larvae (FFML) or hydrolysate mealworm larvae (HML) (Tenebrio molitor) as a substitute for spray-dried plasma protein (SDPP) as a… read more here.
Keywords: hydrolysate mealworm; sdpp; con; hml ... See more keywords
p53 Binding Sites in Long Terminal Repeat 5Hs (LTR5Hs) of Human Endogenous Retrovirus K Family (HML-2 Subgroup) Play Important Roles in the Regulation of LTR5Hs Transcriptional Activity
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00485-22
Abstract: Human endogenous retroviruses (HERVs) were integrated into the human genome in ancient times and have been coevolving with the host. Since the Human Genome Project, HERVs have attracted increasing attention. ABSTRACT The long terminal repeats… read more here.
Keywords: human endogenous; transcriptional activity; hml; activity ... See more keywords
Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors.
Sign Up to like & getrecommendations! Published in 2020 at "JCI insight"
DOI: 10.1172/jci.insight.131093
Abstract: Although human endogenous retroviruses (HERVs) represent a substantial proportion of the human genome and some HERVs, such as HERV-K(HML-2), are reported to be involved in neurological disorders, little is known about their biological function. We… read more here.
Keywords: human endogenous; hml rna; hml; herv hml ... See more keywords