Exosomal lncRNA HMMR-AS1 mediates macrophage polarization through miR-147a/ARID3A axis under hypoxia and affects the progression of hepatocellular carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental toxicology"
DOI: 10.1002/tox.23489
Abstract: BACKGROUND At present, the role of lncRNA in different kinds of tumors has been widely reported, but its role with hypoxic environment and macrophage polarization is still unclear. Therefore, this study tried to clarify the… read more here.
Keywords: hmmr; lncrna hmmr; macrophage polarization; hmmr as1 ... See more keywords
hmmr mediates anterior neural tube closure and morphogenesis in the frog Xenopus.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.07.020
Abstract: Development of the central nervous system requires orchestration of morphogenetic processes which drive elevation and apposition of the neural folds and their fusion into a neural tube. The newly formed tube gives rise to the… read more here.
Keywords: anterior neural; tube; hmmr; neural tube ... See more keywords
The nonmotor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e17-08-0531
Abstract: The nonmotor adaptor protein HMMR maintains the kinetics and integrity of chromosome segregation by promoting TPX2-Eg5 complexes that dampen Eg5-mediated forces and support K-fiber stability, kinetochore–microtubule attachments, and inter-kinetochore tension. HMMR is needed to prevent… read more here.
Keywords: kinetics integrity; hmmr; eg5 mediated; chromosome segregation ... See more keywords
Increased expression of HMMR in renal cell carcinoma is an independent prognostic factor
Sign Up to like & getrecommendations! Published in 2022 at "Oncology Letters"
DOI: 10.3892/ol.2022.13614
Abstract: The present study investigated how abnormal expression of hyaluronan-mediated mobility receptor (HMMR) in renal cell carcinoma (RCC) tissue affects the growth of RCC cells and the association between expression of HMMR and pathological staging and… read more here.
Keywords: cell; hmmr; independent prognostic; rcc ... See more keywords
Oleate acid-stimulated HMMR expression by CEBPα is associated with nonalcoholic steatohepatitis and hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.49785
Abstract: Non-alcoholic steatohepatitis (NASH) is a type of nonalcoholic fatty liver disease and has become a major risk factor for hepatocellular carcinoma (HCC). However, the underlying pathophysiological mechanisms are still elusive. Here, we identify hyaluronan-mediated motility… read more here.
Keywords: hepatocellular carcinoma; hcc; nash hcc; cebp ... See more keywords