The role of lipid rafts in cell entry of human metapneumovirus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Medical Virology"
DOI: 10.1002/jmv.25414
Abstract: Human metapneumovirus (hMPV) is a crucial pathogen in children. A cell entry is the first step for infection. Our previous study indicated that there was an endocytosis pathway for hMPV cell entry. Lipid raft is… read more here.
Keywords: hmpv; role; cell entry; entry ... See more keywords
Report of death in children with SARS‐CoV‐2 and Human metapneumovirus (hMPV) co‐infection: is hMPV the trigger?
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Virology"
DOI: 10.1002/jmv.26401
Abstract: Abstract In the last month of 2019, a new virus called SARS‐CoV‐2 was discovered in Wuhan, China. This virus causes a wide range of symptoms, and respiratory tract illness is the most common disorder. To… read more here.
Keywords: hmpv; cov human; sars cov; virus ... See more keywords
The A2c111nt‐dup variants of human metapneumovirus predominantly circulating in Qingdao, China, during 2018 and 2019
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.27888
Abstract: Human metapneumovirus (HMPV) plays an important role in acute respiratory tract infections (ARTIs), especially in children. We investigated the epidemiology of HMPV associated with ARTIs among pediatric inpatients and identified HMPV genetic variations in Qingdao,… read more here.
Keywords: human metapneumovirus; hmpv; qingdao china; a2c111nt dup ... See more keywords
Epidemiology and genetic characterization of human metapneumovirus in pediatric patients from Hangzhou China
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medical Virology"
DOI: 10.1002/jmv.28024
Abstract: Human metapneumovirus (HMPV), which is distributed worldwide, is a significant viral respiratory pathogen responsible for causing acute respiratory tract infections (ARTIs) in children. The aim of the present study was to investigate the epidemiological and… read more here.
Keywords: human metapneumovirus; hmpv; patients hangzhou; pediatric patients ... See more keywords
Development and optimization of a direct plaque assay for trypsin-dependent human metapneumovirus strains.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2018.05.012
Abstract: Human metapneumovirus (HMPV) is a non-segmented, negative strand RNA virus belonging to the family Pneumoviridae, previously a subfamily of Paramyxoviridae. It is a leading cause of lower respiratory tract infection in infants, children, and adults… read more here.
Keywords: hmpv; plaque assay; direct plaque; human metapneumovirus ... See more keywords
Prevalence of Human Metapneumovirus Infections in Iran: A Systematic Review and Meta-Analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Fetal and pediatric pathology"
DOI: 10.1080/15513815.2020.1725939
Abstract: Background: We sought to systematically review the literature and perform a meta-analysis by assessing the prevalence of human metapneumovirus (hMPV) infections from a number of studies conducted in Iran. Methods: Entire studies addressing epidemiology of… read more here.
Keywords: prevalence human; hmpv; prevalence; human metapneumovirus ... See more keywords
Human Metapneumovirus Infection and Genotyping of Infants in Rural Nepal.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piaa118
Abstract: BACKGROUND Acute respiratory tract infections are a serious clinical burden in infants; human metapneumovirus (HMPV) is an important etiological agent. We investigated genotypic variation and molecular epidemiological patterns among infants infected with HMPV in Sarlahi,… read more here.
Keywords: metapneumovirus infection; hmpv; rural nepal; infection genotyping ... See more keywords
Drug Repurposing for Therapeutic Discovery against Human Metapneumovirus Infection
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01008-22
Abstract: Human metapneumovirus (HMPV) is recognized as an important cause of pneumonia in infants, in the elderly, and in immunocompromised individuals worldwide. The absence of an antiviral treatment or vaccine strategy against HMPV infection creates a… read more here.
Keywords: human metapneumovirus; infection; drug repurposing; hmpv ... See more keywords
Structure, Immunogenicity, and Conformation-Dependent Receptor Binding of the Postfusion Human Metapneumovirus F Protein
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Virology"
DOI: 10.1128/jvi.00593-21
Abstract: Human metapneumovirus (hMPV) is an important cause of viral respiratory disease. In this paper, we report the X-ray crystal structure of the hMPV fusion (F) protein in the postfusion conformation from genotype B. ABSTRACT Human… read more here.
Keywords: human metapneumovirus; conformation; postfusion; hmpv ... See more keywords
Human Metapneumovirus Phosphoprotein Independently Drives Phase Separation and Recruits Nucleoprotein to Liquid-Like Bodies
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01099-22
Abstract: Human metapneumovirus (HMPV) is a leading cause of respiratory disease among children, immunocompromised individuals, and the elderly. Currently, no vaccines or antivirals are available for the treatment of HMPV infections. ABSTRACT Human metapneumovirus (HMPV) inclusion… read more here.
Keywords: hmpv; phase separation; human metapneumovirus;
Emergence and Potential Extinction of Genetic Lineages of Human Metapneumovirus between 2005 and 2021
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02280-22
Abstract: Human metapneumovirus (HMPV) is one of the major causative agents of human respiratory tract infections. Monitoring of virus evolution could aid toward the development of new antiviral treatments or vaccine designs. ABSTRACT Human metapneumovirus (HMPV)… read more here.
Keywords: general practitioners; human metapneumovirus; genetic lineages; 2005 2021 ... See more keywords