An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses
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DOI: 10.1128/msphere.00062-23
Abstract: Analysis of the viral lineages responsible for the 2022 monkeypox outbreak suggested that APOBEC enzymes are driving hMPXV1 evolution. Using 1,624 public sequences, we analyzed the mutations that accumulated between 2017 and the emergence of… read more here.
Keywords: hmpxv1; infecting orthopoxviruses; outbreak; virus ... See more keywords