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   Articles with "hmsc" as a keyword



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Feasibility of defined, animal component free, protein free, salt base freezing solution composed of 5% DMSO for cryopreservation of HMSC toward clinical applications

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recommendations! Published in 2020 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2020.03.140

Abstract: Background & Aim hMSC are a critical raw material for cell-based therapies and usually a large number of cells are required for clinical applications. Cryopreservation is currently the only method to preserve cells with maintained… read more here.

Keywords: composed dmso; hmsc; salt base; clinical applications ... See more keywords
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MicroRNA-3148 acts as molecular switch promoting malignant transformation and adipocytic differentiation of immortalized human bone marrow stromal cells via direct targeting of the SMAD2/TGFβ pathway

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recommendations! Published in 2020 at "Cell Death Discovery"

DOI: 10.1038/s41420-020-00312-z

Abstract: MicroRNAs (miRs/miRNAs) play a key role in posttranscriptional regulation of gene expression and are implicated in a number of physiological and pathological conditions, including cellular malignant transformation. In the current study, we investigated the role… read more here.

Keywords: mir; hmsc; transformation; expression ... See more keywords

The Restoring Effect of Human Umbilical Cord-Derived Mesenchymal Cell-Conditioned Medium (hMSC-CM) against Carbon Tetrachloride-Induced Pulmonary Fibrosis in Male Wistar Rats

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recommendations! Published in 2022 at "International Journal of Inflammation"

DOI: 10.1155/2022/7179766

Abstract: Objective Pulmonary toxicity induced by CCl4, a model of idiopathic pulmonary fibrosis (IPF), leads to tissue remodeling and inflammation. Human umbilical cord mesenchymal cell-conditioned medium (hMSC-CM) is a potent anti-inflammatory, antioxidative, and antifibrotic agent. Methods… read more here.

Keywords: control; hmsc; pulmonary fibrosis; group ... See more keywords
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Autologous Mesenchymal Stroma Cells Are Superior to Allogeneic Ones in Bone Defect Regeneration

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recommendations! Published in 2018 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms19092526

Abstract: The application of autologous mesenchymal stem cells (MSC) for the treatment of bone defects requires two invasive procedures and several weeks of ex vivo cell expansion. To overcome these limitations, the administration of allogeneic MSC… read more here.

Keywords: hmsc; bone defect; regeneration; bone ... See more keywords
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99mTc-HDP Labeling—A Non-Destructive Method for Real-Time Surveillance of the Osteogenic Differentiation Potential of hMSC during Ongoing Cell Cultures

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232415874

Abstract: 99-Metastabil Technetium (99mTc) is a radiopharmaceutical widely used in skeletal scintigraphy. Recent publications show it can also be used to determine the osteogenic potential of human mesenchymal stem cells (hMSCs) by binding to hydroxyapatite formed… read more here.

Keywords: non destructive; hmsc; osteogenic differentiation; real time ... See more keywords