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   Articles with "hmscs" as a keyword



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DJ‐1 Regulates Differentiation of Human Mesenchymal Stem Cells into Smooth Muscle‐like Cells in Response to Sphingosylphosphorylcholine

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recommendations! Published in 2017 at "PROTEOMICS"

DOI: 10.1002/pmic.201700208

Abstract: Although multiple factors contribute to the differentiation of human mesenchymal stem cells (hMSCs) into various types of cells, the differentiation of hMSCs into smooth muscle cells (SMCs), one of central events in vascular remodeling, remains… read more here.

Keywords: hmscs; response; differentiation; smooth muscle ... See more keywords
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A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells

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recommendations! Published in 2017 at "STEM CELLS"

DOI: 10.1002/stem.2549

Abstract: The clinical effectiveness of systemically administered human mesenchymal stem cells (hMSCs) depends on their capacity to engage vascular endothelium. hMSCs derived from bone marrow (BM‐hMSCs) natively lack endothelial binding capacity, but express a CD44 glycovariant… read more here.

Keywords: hmscs; human mesenchymal; cd44; expression ... See more keywords
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Construction of multicellular aggregate by E-cadherin coated microparticles enhancing the hepatic specific differentiation of mesenchymal stem cells.

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recommendations! Published in 2019 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2019.01.030

Abstract: The differentiation of human mesenchymal stem cells (hMSCs) into hepatocyte-like cells in vitroprovides a promising candidate for cell therapy of liver diseases, and cell aggregates have been proposed to improve the efficiency of expansion and… read more here.

Keywords: stem cells; hmscs; cad; differentiation ... See more keywords
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VE-cadherin functionalized injectable PAMAM/HA hydrogel promotes endothelial differentiation of hMSCs and vascularization

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recommendations! Published in 2020 at "Applied Materials Today"

DOI: 10.1016/j.apmt.2020.100690

Abstract: Abstract The functionalization of hydrogels for tissue engineering mainly focuses on the modification of hydrogels with extracellular matrices (ECM) and growth factors to promote vascularization by bio-mimicking vascular extracellular microenvironment. However, the lack of cell-cell… read more here.

Keywords: hmscs; vascularization; hydrogel; cell ... See more keywords
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towards stem cell therapy of polycystic ovary syndrome (PCOS): therapeutic effect of human mesenchymal stem cells transplantation in pcos mouse model by regulating ovarian vascularization

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recommendations! Published in 2019 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2019.03.484

Abstract: Background & Aim Background Women with the polycystic ovarian syndrome (PCOS) have an increase in ovarian androgen production. Recent studies report that angiogenesis is aberrantly increased in ovaries of PCOS patients. Angiogenesis play an important… read more here.

Keywords: pcos; hmscs; mesenchymal stem; human mesenchymal ... See more keywords
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Epigenetic regulation of miR-29a/miR-30c/DNMT3A axis controls SOD2 and mitochondrial oxidative stress in human mesenchymal stem cells

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recommendations! Published in 2020 at "Redox Biology"

DOI: 10.1016/j.redox.2020.101716

Abstract: The use of human mesenchymal stem cells (hMSCs) in clinical applications requires large-scale cell expansion prior to administration. However, the prolonged culture of hMSCs results in cellular senescence, impairing their proliferation and therapeutic potentials. To… read more here.

Keywords: hmscs; mir 29a; mir; senescence ... See more keywords
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TEMPO-Conjugated Gold Nanoparticles for Reactive Oxygen Species Scavenging and Regulation of Stem Cell Differentiation.

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recommendations! Published in 2017 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.7b12486

Abstract: Controlling the differentiation of human mesenchymal stem cells (hMSCs) shows a great potential in regenerative medicine. Because overproduced reactive oxygen species (ROS) have an obvious inhibitory effect on the differentiation and functions of hMSCs, it… read more here.

Keywords: stem cell; hmscs; differentiation; tempo ... See more keywords
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Cas9-AAV6-engineered human mesenchymal stromal cells improved cutaneous wound healing in diabetic mice

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recommendations! Published in 2020 at "Nature Communications"

DOI: 10.1038/s41467-020-16065-3

Abstract: Human mesenchymal stromal cells (hMSCs) are a promising source for engineered cell-based therapies in which genetic engineering could enhance therapeutic efficacy and install novel cellular functions. Here, we describe an optimized Cas9-AAV6-based genome editing tool… read more here.

Keywords: cas9 aav6; wound healing; human mesenchymal; mesenchymal stromal ... See more keywords
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Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-22855-z

Abstract: Aging is a complex biological process, which involves multiple mechanisms with different levels of regulation. Senescent cells are known to secrete senescence-associated proteins, which exert negative influences on surrounding cells. Mesenchymal stem cells (MSCs), the… read more here.

Keywords: hmscs; analysis; stem; osteogenesis ... See more keywords
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The importance of cellular and exosomal miRNAs in mesenchymal stem cell osteoblastic differentiation

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recommendations! Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-85306-2

Abstract: The differentiation of osteoblasts is under complex regulation that includes autocrine and paracrine signaling from MSCs. Exosomes are important components of the MSC secretome and their cargo contains numerous miRNAs. In this study, the importance… read more here.

Keywords: hmscs; importance; osteoblastic differentiation; hmsc exosomes ... See more keywords
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Hii regions and high-mass starless clump candidates. II. Fragmentation and induced star formation at ~0:025 pc scale: An ALMA continuum study

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recommendations! Published in 2020 at "Astronomy and Astrophysics"

DOI: 10.1051/0004-6361/202038421

Abstract: The ionization feedback from HII regions modifies the properties of high-mass starless clumps (HMSCs, of several hundred to a few thousand solar masses with a size of ~0.1-1 pc), such as temperature and turbulence, on… read more here.

Keywords: hmscs; hii regions; 025 scale; mass ... See more keywords