Inhibition of adamts13: a novel therapy to treat mechanical circulatory support-induced acquired von willebrand syndrome
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DOI: 10.1093/ehjci/ehaa946.3836
Abstract: Bleeding is the most frequent adverse event in patients with continuous flow mechanical circulatory support (CF-MCS) and has been linked to the occurrence of acquired von Willebrand syndrome (aVWS). MCS devices cause an increased shear-induced… read more here.
Keywords: impella; vwf multimers; von willebrand; hmw vwf ... See more keywords
Prognostic Impact of High-Molecular-Weight von Willebrand Factor Multimer Ratio in Classical Low-Flow Low-Gradient Aortic Stenosis
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DOI: 10.1159/000539731
Abstract: Abstract Introduction: High-molecular-weight (HMW) von Willebrand factor (VWF) multimer deficiency occurs in classical low-flow, low-gradient (LF/LG) aortic stenosis (AS) due to shear force-induced proteolysis. The prognostic value of HMW VWF multimer deficiency is unknown. Therefore,… read more here.
Keywords: vwf multimer; hmw vwf; multimer ratio; multimer ... See more keywords