Simultaneous Quantification of a Novel β-Carboline Alkaloid Derivative and Its Three Metabolites in Rat Plasma by UHPLC-MS/MS and Its Application to a Pharmacokinetic Study.
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DOI: 10.1002/jssc.70282
Abstract: 1-Methyl-9-(3-pyridinylmethyl)-9H-pyrido[3,4-b] indole (HMYB) is a novel semi-synthetic alkaloid derived from β-carboline harmane, which has been proven to be effective in treatment of encopresis. But the pharmacokinetic characteristics of HMYB were not yet illustrated. In this… read more here.
Keywords: hmyb three; hmyb; pharmacokinetic study; three metabolites ... See more keywords