Synthesis and evaluation of benzenesulfonic acid derivatives as human neutrophil elastase (hNE) inhibitors
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DOI: 10.1007/s00044-020-02684-4
Abstract: Herein we report our investigation concerning the development of Human neutrophil elastase (hNE) inhibitors for the treatment of Acute Respiratory Distress Syndrome (ARDS). Various benzenesulfonic acid derived compounds were synthesized and evaluated as competitive inhibitors… read more here.
Keywords: benzenesulfonic acid; neutrophil elastase; human neutrophil; hne ... See more keywords