β3-Adrenergic receptor regulates hepatic apolipoprotein A-I gene expression.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of clinical lipidology"
DOI: 10.1016/j.jacl.2017.07.007
Abstract: BACKGROUND β3-adrenergic receptor (β3-AR) was shown to upregulate hepatic apolipoprotein A-I (apoA-I) expression and reverse atherosclerotic plaques in vivo experiments. However, the effect of β3-AR on apoA-I expression in vitro is unknown. The specific mechanism underlying β3-AR… read more here.
Keywords: apoa expression; hnf; expression; apoa promoter ... See more keywords
Xanthohumol suppresses NPC1L1 gene expression through down-regulation of HNF-4α and inhibits cholesterol uptake in Caco-2 cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.9b05221
Abstract: Xanthohumol (Xan) is a prenylated chalcone mainly found in hops, it has been demonstrated to function against hypercholesterolemia, hyperlipidemia, and atherosclerosis. In this study, we focused on the hypocholesterolemic effect of Xan on cholesterol uptake… read more here.
Keywords: caco cells; xan; hnf; expression ... See more keywords
LncRNA4474 inhibits renal fibrosis by regulating hepatocyte nuclear factor-1β through miR-615 modulation
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2046982
Abstract: ABSTRACT Long noncoding RNAs (lncRNAs) and microRNAs (miRNAs) are involved in the development and progression of renal fibrosis. lncRNAs can regulate target messenger RNAs (mRNAs) by competitively binding to miRNAs. However, research on lncRNA–miRNA–mRNA interactions… read more here.
Keywords: lncrna4474; renal fibrosis; hnf; expression ... See more keywords
HNF: Hybrid Neural Filtering Based on Centrality-Aware Random Walk for Personalized Recommendation
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Network Science and Engineering"
DOI: 10.1109/tnse.2021.3100864
Abstract: Social computing which analyzes users’ behaviors can help personalized recommender system to extract preferences of users. Most of personalized recommender systems exploit a user-item rating matrix to learn representations of users and items for predicting… read more here.
Keywords: recommendation; user item; hnf; neural filtering ... See more keywords
Identification of Angiogenic Cargoes in Human Fibroblasts-Derived Extracellular Vesicles and Induction of Wound Healing
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15060702
Abstract: A complete redevelopment of the skin remains a challenge in the management of acute and chronic wounds. Recently, the application of extracellular vesicles (EVs) for soft tissue wound healing has received much attention. As fibroblasts… read more here.
Keywords: skin; extracellular vesicles; wound healing; hnf ... See more keywords
Roles and mechanisms of action of HNF‑4α in the hepatic differentiation of WB‑F344 cells.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of molecular medicine"
DOI: 10.3892/ijmm.2018.4010
Abstract: Hepatocyte nuclear factor 4 α (HNF‑4α) is a nuclear receptor and mediates hepatic genes. WB‑F344 liver epithelial cells can differentiate into hepatocytes. The present study aimed to examine the roles and mechanisms of action of… read more here.
Keywords: hnf; cell; f344 cells; differentiation f344 ... See more keywords
HNF-4α downregulation promotes tumor migration and invasion by regulating E-cadherin in renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Oncology Reports"
DOI: 10.3892/or.2019.7214
Abstract: Renal cell carcinoma (RCC) is the most common malignant disease of the kidneys in adults. Patients with metastatic RCC have an unusually poor prognosis and exhibit resistance to all current therapies. Therefore, it is necessary… read more here.
Keywords: hnf downregulation; renal cell; cell carcinoma; hnf ... See more keywords