MYC‐activated lncRNA HNF1A‐AS1 overexpression facilitates glioma progression via cooperating with miR‐32‐5p/SOX4 axis
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DOI: 10.1002/cam4.3186
Abstract: Mounting literatures have revealed the crucial effects of long noncoding RNA (lncRNA) in various cancers, including glioma. HNF1A‐AS1, a novel lncRNA, is reported to modulate tumorigenesis and development of multiple cancers. However, the tumorigenic function… read more here.
Keywords: glioma; sox4; as1; hnf1a as1 ... See more keywords
Differential expression of HNF1A and HNF1A‐AS1 in colon cancer cells
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DOI: 10.1002/iub.2609
Abstract: The human hepatocyte nuclear factor 1 homeobox A (HNF1A) gene loci express the protein‐coding HNF1A transcript and a long non‐coding RNA in the anti‐sense (HNF1A‐AS1) direction. HNF1A‐AS1 is expressed in numerous types of cancers and… read more here.
Keywords: hnf1a hnf1a; hnf1a as1; rna; hnf1a ... See more keywords
The HNF1A-AS1/miR-92a-3p axis affects the radiosensitivity of non-small cell lung cancer by competitively regulating the JNK pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09595-z
Abstract: BACKGROUND It has been widely reported that long non-coding RNAs (lncRNAs) could affect the varieties of tumor response to radiotherapy. LncRNA HNF1A-AS1 is transcribed from HNF1A gene cluster's antisense strand. This work focused on the… read more here.
Keywords: nsclc; as1 mir; as1; hnf1a as1 ... See more keywords
Long non-coding RNA HNF1A-AS1 induces 5-FU resistance of gastric cancer through miR-30b-5p/EIF5A2 pathway
Sign Up to like & getrecommendations! Published in 2022 at "Translational Oncology"
DOI: 10.1016/j.tranon.2022.101351
Abstract: Highlights • HNF1A-AS1 promotes 5-FU resistance in gastric cancer cells.• HNF1A-AS1 regulates EIF5A2 expression through sponging miR-30b-5p.• HNF1A-AS1 promotes EMT process and 5-FU resistance through miR-30b-5p/EIF5A2 pathway.• HNF1A-AS1 promotes 5-FU resistance in gastric cancer in… read more here.
Keywords: gastric cancer; mir 30b; resistance gastric; hnf1a as1 ... See more keywords
Prognostic and clinical significance of long non-coding RNA HNF1A-AS1 in solid cancers
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DOI: 10.1097/md.0000000000018264
Abstract: Abstract Background: LncRNA HNF1A Antisense RNA 1 (HNF1A-AS1) is often dysregulated in cancer. We performed this meta-analysis to clarify the usefulness of HNF1A-AS1 as a prognostic marker in malignant tumors. Methods: The PubMed, OVID, and… read more here.
Keywords: hnf1a as1; as1 expression; hnf1a; rna hnf1a ... See more keywords
GATA1-Activated HNF1A-AS1 Facilitates the Progression of Triple-Negative Breast Cancer via Sponging miR-32-5p to Upregulate RNF38
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DOI: 10.2147/cmar.s274204
Abstract: Background Triple-negative breast cancer (TNBC) is a highly invasive subtype of breast cancer with a high mortality rate. Recently, long non-coding RNAs (lncRNAs) are confirmed to modulate the progression of assorted cancers, including TNBC. However,… read more here.
Keywords: hnf1a as1; tnbc; breast cancer; rnf38 ... See more keywords
HNF1A-AS1：A tumor-associated long non-coding RNA.
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DOI: 10.2174/1381612828666220520113846
Abstract: BACKGROUND Hepatocyte nuclear factor 1 homeobox A antisense RNA 1 (HNF1A-AS1) is a Long non-coding RNA（LncRNA）that participates in the occurrence development of lots of tumors and is supposed to be a new biomarker. The text… read more here.
Keywords: hnf1a as1; rna; hnf1a; tumor ... See more keywords
sh-HNF1A-AS1 reduces the epithelial-mesenchymal transition and stemness of esophageal cancer cells.
Sign Up to like & getrecommendations! Published in 2022 at "Neoplasma"
DOI: 10.4149/neo_2022_211102n1555
Abstract: HNF1A-AS1 is a cancer-related lncRNA. Elevated expression of HNF1A-AS1 has been observed in various malignancies including esophageal squamous cell carcinoma (ESCC). However, the role of HNF1A-AS1 in ESCC has not been fully understood. This study… read more here.
Keywords: hnf1a as1; mir 298; stemness; expression ... See more keywords